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Auke Verhaar

Explore the profile of Auke Verhaar including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 277
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Recent Articles
1.
Su J, Li F, Wang Y, Su Y, Verhaar A, Ma Z, et al.
Front Nutr . 2022 May; 9:832757. PMID: 35634379
Recently we reported that in healthy volunteer Ramadan-associated intermittent fasting (RAIF) remodels the gut microbiome and resulted in an increase in small chain fatty acid producing bacteria concomitant with improved...
2.
Su J, Braat H, Verhaar A, Peppelenbosch M
Front Pharmacol . 2022 Feb; 13:843133. PMID: 35222050
No abstract available.
3.
Mondanelli G, Bianchi R, Pallotta M, Orabona C, Albini E, Iacono A, et al.
Immunity . 2017 Feb; 46(2):233-244. PMID: 28214225
Arginase 1 (Arg1) and indoleamine 2,3-dioxygenase 1 (IDO1) are immunoregulatory enzymes catalyzing the degradation of l-arginine and l-tryptophan, respectively, resulting in local amino acid deprivation. In addition, unlike Arg1, IDO1...
4.
Parikh K, Diks S, Tuynman J, Verhaar A, Lowenberg M, Hommes D, et al.
PLoS One . 2009 Aug; 4(7):e6440. PMID: 19649278
Kinases are pivotal regulators of cellular physiology. The human genome contains more than 500 putative kinases, which exert their action via the phosphorylation of specific substrates. The determinants of this...
5.
Ritsema T, Hernandez L, Verhaar A, Altenbach D, Boller T, Wiemken A, et al.
Plant J . 2006 Oct; 48(2):228-37. PMID: 17018033
Fructans are fructose polymers that are synthesized from sucrose by fructosyltransferases. Fructosyltransferases are present in unrelated plant families suggesting a polyphyletic origin for their transglycosylation activity. Based on sequence comparisons...
6.
Lowenberg M, Scheffer M, Verhaar A, Peppelenbosch M, Hommes D
Inflamm Bowel Dis . 2006 Jun; 12(7):665. PMID: 16804404
No abstract available.
7.
Lowenberg M, Tuynman J, Scheffer M, Verhaar A, Vermeulen L, van Deventer S, et al.
Endocrinology . 2006 Apr; 147(7):3555-62. PMID: 16574792
Glucocorticoids (GCs) are powerful immunosuppressive agents that control genomic effects through GC receptor (GR)-dependent transcriptional changes. A common complication of GC therapy is insulin resistance, but the underlying molecular mechanism...
8.
Ritsema T, Verhaar A, Vijn I, Smeekens S
Plant Mol Biol . 2005 Sep; 58(5):597-607. PMID: 16158237
Enzymes of the glycosyl hydrolase family 32 are highly similar with respect to primary sequence but catalyze divergent reactions. Previously, the importance of the conserved sucrose-binding box in determining product...
9.
Lowenberg M, Verhaar A, van den Blink B, Ten Kate F, van Deventer S, Peppelenbosch M, et al.
J Immunol . 2005 Aug; 175(4):2293-300. PMID: 16081798
There is a substantial need for novel treatment strategies in Crohn's disease (CD), a chronic relapsing inflammatory disease of the gut. In an earlier study, we reported clinical efficacy of...
10.
Ritsema T, Verhaar A, Vijin I, Smeekens S
Plant Mol Biol . 2004 Dec; 54(6):853-63. PMID: 15604656
The onion fructosyltransferase fructan:fructan 6G-fructosyltransferase (6G-FFT) synthesizes fructans of the inulin neo-series using 1-kestose as a substrate. 6G-FFT couples a fructosyl residue to either the terminal glucose via a beta...