Audrius Paskevicius
Overview
Explore the profile of Audrius Paskevicius including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
459
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0
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Recent Articles
1.
Steen S, Paskevicius A, Liao Q, Steen E
Scand Cardiovasc J
. 2024 Oct;
58(1):2418084.
PMID: 39460683
. The aim was to demonstrate a reliable method to test the function of the whole heart. . Pigs of varying sizes (44-80 kg) were exposed to dose response of...
2.
Bender M, Abicht J, Reichart B, Neumann E, Radan J, Mokelke M, et al.
Biomedicines
. 2024 Aug;
12(8.
PMID: 39200391
The blockade of the CD40/CD40L immune checkpoint is considered essential for cardiac xenotransplantation. However, it is still unclear which single antibody directed against CD40 or CD40L (CD154), or which combination...
3.
Bender M, Abicht J, Reichart B, Leuschen M, Wall F, Radan J, et al.
Biomedicines
. 2024 Jun;
12(6.
PMID: 38927543
Cardiac xenotransplantation has seen remarkable success in recent years and is emerging as the most promising alternative to human cardiac allotransplantation. Despite these achievements, acute vascular rejection still presents a...
4.
Langin M, Buttgereit I, Reichart B, Panelli A, Radan J, Mokelke M, et al.
Transplantation
. 2023 Aug;
107(12):e328-e338.
PMID: 37643028
Background: Orthotopic cardiac xenotransplantation has seen substantial advancement in the last years and the initiation of a clinical pilot study is close. However, donor organ overgrowth has been a major...
5.
Pigot H, Soltesz K, Paskevicius A, Liao Q, Sjoberg T, Steen S
Artif Organs
. 2022 May;
46(9):1794-1803.
PMID: 35548921
Background: Existing working heart models for ex vivo functional evaluation of donor hearts often use cardiac afterloads made up of discrete resistive and compliant elements. This approach limits the practicality...
6.
Langin M, Reichart B, Steen S, Sjoberg T, Paskevicius A, Liao Q, et al.
Xenotransplantation
. 2020 Aug;
28(1):e12636.
PMID: 32841431
Background: Successful preclinical transplantations of porcine hearts into baboon recipients are required before commencing clinical trials. Despite years of research, over half of the orthotopic cardiac xenografts were lost during...
7.
Nilsson J, Jernryd V, Qin G, Paskevicius A, Metzsch C, Sjoberg T, et al.
Nat Commun
. 2020 Jun;
11(1):2976.
PMID: 32532991
Pre-clinical heart transplantation studies have shown that ex vivo non-ischemic heart preservation (NIHP) can be safely used for 24 h. Here we perform a prospective, open-label, non-randomized phase II study...
8.
Reichart B, Langin M, Radan J, Mokelke M, Buttgereit I, Ying J, et al.
J Heart Lung Transplant
. 2020 Jun;
39(8):751-757.
PMID: 32527674
Background: The demand for donated human hearts far exceeds the number available. Xenotransplantation of genetically modified porcine organs provides an alternative. In 2000, an Advisory Board of the International Society...
9.
Langin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, et al.
Nature
. 2019 Apr;
568(7752):E7.
PMID: 30944481
In this Letter, Mayuko Kurome and Valeri Zakhartchenko have been added to the author list (affiliated with Institute of Molecular Animal Breeding and Biotechnology, Gene Center, LMU Munich, Munich, Germany)....
10.
Soltesz K, Paskevicius A, Pigot H, Liao Q, Sjoberg T, Steen S
Resuscitation
. 2019 Mar;
138:215-221.
PMID: 30862527
Purpose: It has previously been shown that continuous intratracheal insufflation of oxygen (CIO) is superior to intermittent positive pressure ventilation (IPPV) regarding gas exchange and haemodynamics. The purpose of this...