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Audrey Thomas-Schoemann

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Articles 43
Citations 464
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Recent Articles
1.
Inouri T, Noel J, Blanchet B, Thomas-Schoemann A
Support Care Cancer . 2024 Sep; 32(10):648. PMID: 39254772
Concomitant direct oral anticoagulants (DOACs) and tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor (anti-VEGF TKI) have been associated with a higher risk of bleeding. Nevertheless, concomitant administration seems...
2.
Bonnet M, Jouinot A, Boudou-Rouquette P, Seif V, Villeminey C, Arrondeau J, et al.
Eur J Clin Pharmacol . 2023 Mar; 79(5):635-641. PMID: 36951965
Purpose: Pemetrexed has shown efficacy as monotherapy or in combination with platinum salts in the treatment of non-small cell lung cancer and mesothelioma. However, severe hematological toxicities induced by pemetrexed-based...
3.
Monribot A, Huillard O, Khoudour N, Preta L, Blanchet B, Cabanes L, et al.
Br J Clin Pharmacol . 2023 Jan; 89(4):1486-1490. PMID: 36709977
This case report describes a pharmacokinetic drug-drug interaction between crizotinib, a tyrosine kinase inhibitor, and sofosbuvir/velpatasvir, a direct-acting antiviral drug, leading to cardiac toxicity. A 75-year-old man, with no cardiovascular...
4.
Minot-This M, Boudou-Rouquette P, Jouinot A, De Percin S, Balakirouchenane D, Khoudour N, et al.
Pharmaceutics . 2022 Jun; 14(6). PMID: 35745797
Background: Pazopanib (PAZ) is an oral angiogenesis inhibitor approved to treat soft tissue sarcoma (STS) but associated with a large interpatient pharmacokinetic (PK) variability and narrow therapeutic index. We aimed...
5.
Bellesoeur A, Gataa I, Jouinot A, Mershati S, Piketty A, Tlemsani C, et al.
Cancer Chemother Pharmacol . 2021 Jul; 88(4):741-751. PMID: 34304283
Background: The risk of drug-drug interactions (DDI) has become a major issue in cancer patients. However, data in sarcoma patients are scarce. We aimed to evaluate the frequency and the...
6.
Slimano F, Baudouin A, Zerbit J, Toulemonde-Deldicque A, Thomas-Schoemann A, Chevrier R, et al.
Cancer Treat Rev . 2020 Jul; 88:102063. PMID: 32623296
The Coronavirus disease (COVID-19) pandemic is disrupting our health environment. As expected, studies highlighted the great susceptibility of cancer patients to COVID-19 and more severe complications, leading oncologists to deeply...
7.
Meyo M, Jouinot A, Giroux-Leprieur E, Fabre E, Wislez M, Alifano M, et al.
Cancers (Basel) . 2020 Feb; 12(2). PMID: 32085544
A large interindividual variability has been observed in anti Programmed cell Death 1 (anti-PD1) therapies efficacy. The aim of this study is to assess the correlation of soluble PD-1 (sPD-1),...
8.
Hirsch L, Bellesoeur A, Boudou-Rouquette P, Arrondeau J, Thomas-Schoemann A, Kirchgesner J, et al.
Eur J Cancer . 2019 Dec; 124:170-177. PMID: 31794927
Background: The occurrence of severe, acute limiting toxicity in patients receiving anti-programmed cell death receptor-1 monoclonal antibodies, such as nivolumab, is largely unpredictable. Sarcopenia was found to be associated with...
9.
Bellesoeur A, Ollier E, Allard M, Hirsch L, Boudou-Rouquette P, Arrondeau J, et al.
Cancers (Basel) . 2019 Nov; 11(11). PMID: 31766292
Pharmacokinetic/pharmacodynamic data from real-world cohort are sparse in non small-cell lung cancer (NSCLC) patients treated with nivolumab. The aim of this prospective observational study was to explore the exposure-response relationship...
10.
Noe G, Bellesoeur A, Golmard L, Thomas-Schoemann A, Boudou-Rouquette P, Meyo M, et al.
Cancers (Basel) . 2019 Jun; 11(6). PMID: 31159331
In the era of precision medicine, research of biomarkers for identification of responders to nivolumab therapy is a major challenge. Peripheral blood mononuclear cells (PBMC) could be an interesting surrogate...