Aude Pascal
Overview
Explore the profile of Aude Pascal including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
255
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Recent Articles
1.
Gallaud E, Richard-Parpaillon L, Bataille L, Pascal A, Metivier M, Archambault V, et al.
PLoS Genet
. 2022 Apr;
18(4):e1010145.
PMID: 35377889
The maintenance of a restricted pool of asymmetrically dividing stem cells is essential for tissue homeostasis. This process requires the control of mitotic progression that ensures the accurate chromosome segregation....
2.
Pascal A, Gallaud E, Giet R, Benaud C
J Cell Sci
. 2022 Apr;
135(9).
PMID: 35362526
Proper mitotic spindle orientation depends on the correct anchorage of astral microtubules to the cortex. It relies on the remodeling of the cell cortex, a process not fully understood. Annexin...
3.
Thomas A, Gallaud E, Pascal A, Serre L, Arnal I, Richard-Parpaillon L, et al.
Cell Rep
. 2021 Oct;
37(4):109895.
PMID: 34706235
Neuroblast division is characterized by asymmetric positioning of the cleavage furrow, resulting in a large difference in size between the future daughter cells. In animal cells, furrow placement and assembly...
4.
Metivier M, Gallaud E, Thomas A, Pascal A, Gagne J, Poirier G, et al.
Curr Biol
. 2020 Dec;
31(4):684-695.e6.
PMID: 33259793
Proper assembly of mitotic spindles requires microtubule nucleation not only at the centrosomes but also around chromatin. In this study, we found that the Drosophila tubulin-specific chaperone dTBCE is required...
5.
Metivier M, Monroy B, Gallaud E, Caous R, Pascal A, Richard-Parpaillon L, et al.
Development
. 2019 Apr;
146(8).
PMID: 30936181
Ensconsin (also known as MAP7) controls spindle length, centrosome separation in brain neuroblasts (NBs) and asymmetric transport in oocytes. The control of spindle length by Ensconsin is Kinesin-1 independent but...
6.
Caous R, Pascal A, Rome P, Richard-Parpaillon L, Karess R, Giet R
Nat Commun
. 2015 Nov;
6:8879.
PMID: 26568519
Tissue homeostasis requires accurate control of cell proliferation, differentiation and chromosome segregation. Drosophila sas-4 and aurA mutants present brain tumours with extra neuroblasts (NBs), defective mitotic spindle assembly and delayed...
7.
Ensconsin/Map7 promotes microtubule growth and centrosome separation in Drosophila neural stem cells
Gallaud E, Caous R, Pascal A, Bazile F, Gagne J, Huet S, et al.
J Cell Biol
. 2014 Apr;
204(7):1111-21.
PMID: 24687279
The mitotic spindle is crucial to achieve segregation of sister chromatids. To identify new mitotic spindle assembly regulators, we isolated 855 microtubule-associated proteins (MAPs) from Drosophila melanogaster mitotic or interphasic...
8.
Maciejewska Z, Pascal A, Kubiak J, Ciemerych M
Folia Histochem Cytobiol
. 2011 Nov;
49(3):528-34.
PMID: 22038235
MAP kinases of the ERK family play important roles in oocyte maturation, fertilization, and early embryo development. The role of the signaling pathway involving ERK5 MAP kinase during meiotic and...
9.
Franck N, Montembault E, Rome P, Pascal A, Cremet J, Giet R
PLoS One
. 2011 Feb;
6(1):e14600.
PMID: 21297952
Background: CDK11(p58) is a mitotic protein kinase, which has been shown to be required for different mitotic events such as centrosome maturation, chromatid cohesion and cytokinesis. Methodology/principal Findings: In addition...
10.
Rome P, Montembault E, Franck N, Pascal A, Glover D, Giet R
J Cell Biol
. 2010 May;
189(4):651-9.
PMID: 20479466
Aurora A is a spindle pole-associated protein kinase required for mitotic spindle assembly and chromosome segregation. In this study, we show that Drosophila melanogaster aurora A phosphorylates the dynactin subunit...