Assaf Ezra
Overview
Explore the profile of Assaf Ezra including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
157
Followers
0
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Recent Articles
1.
Somu Naidu G, Rampado R, Sharma P, Ezra A, Kundoor G, Breier D, et al.
ACS Nano
. 2025 Feb;
19(6):6571-6587.
PMID: 39912611
Lipid nanoparticles (LNPs) have emerged as a groundbreaking delivery system for vaccines and therapeutic mRNAs. Ionizable lipids are the most pivotal component of LNPs due to their ability to electrostatically...
2.
Masarwy R, Breier D, Stotsky-Oterin L, Ad-El N, Qassem S, Somu Naidu G, et al.
Adv Sci (Weinh)
. 2024 Dec;
12(7):e2411032.
PMID: 39736115
Squamous cell carcinomas of the head and neck (HNSCC) originate in the upper aerodigestive tract, including the oral cavity, pharynx, and larynx. Current treatments of locally advanced HNSCC often lead...
3.
Rampado R, Somu Naidu G, Karpov O, Goldsmith M, Sharma P, Ezra A, et al.
Adv Sci (Weinh)
. 2024 Nov;
12(3):e2408744.
PMID: 39585189
Lipid Nanoparticles (LNPs) recently emerged as an invaluable RNA delivery platform. With many LNP-based therapeutics in the pre-clinical and clinical pipelines, there is extensive research dedicated to improving LNPs. These...
4.
Shaham-Niv S, Ezra A, Zaguri D, Shotan S, Haimov E, Engel H, et al.
Biophys Chem
. 2024 Mar;
308:107215.
PMID: 38432113
Phenylketonuria is characterized by the accumulation of phenylalanine, resulting in severe cognitive and neurological disorders if not treated by a remarkably strict diet. There are two approved drugs today, yet...
5.
Granot-Matok Y, Ezra A, Ramishetti S, Sharma P, Somu Naidu G, Benhar I, et al.
Theranostics
. 2023 Jul;
13(11):3497-3508.
PMID: 37441597
: Cancer therapy have evolved remarkably over the past decade, providing new strategies to inhibit cancer cell growth using immune modulation, with or without gene therapy. Specifically, suicide gene therapies...
6.
Somu Naidu G, Yong S, Ramishetti S, Rampado R, Sharma P, Ezra A, et al.
Adv Sci (Weinh)
. 2023 Apr;
10(19):e2301929.
PMID: 37092557
Ionizable lipid-based nanoparticles (LNPs) are the most advanced non-viral drug delivery systems for RNA therapeutics and vaccines. However, cell type-specific, extrahepatic mRNA delivery is still a major hurdle, hampering the...
7.
Chatterjee S, Somu Naidu G, Hazan-Halevy I, Grobe H, Ezra A, Sharma P, et al.
Sci Adv
. 2023 Apr;
9(14):eade4800.
PMID: 37018392
The potential of microtubule-associated protein targets for cancer therapeutics remains largely unexplored due to the lack of target-specific agents. Here, we explored the therapeutic potential of targeting cytoskeleton-associated protein 5...
8.
Kon E, Levy Y, Elia U, Cohen H, Hazan-Halevy I, Aftalion M, et al.
Sci Adv
. 2023 Mar;
9(10):eadg1036.
PMID: 36888708
Messenger RNA (mRNA) lipid nanoparticle (LNP) vaccines have emerged as an effective vaccination strategy. Although currently applied toward viral pathogens, data concerning the platform's effectiveness against bacterial pathogens are limited....
9.
Yong S, Ramishetti S, Goldsmith M, Diesendruck Y, Hazan-Halevy I, Chatterjee S, et al.
Adv Mater
. 2022 Jan;
34(13):e2106350.
PMID: 35044699
Chemo-immunotherapy is a combination of "standard-of-care" chemotherapy with immunotherapy and it is considered the most advanced therapeutic modality for various types of cancers. However, many cancer patients still poorly respond...
10.
Gavriel Y, Rabinovich-Nikitin I, Ezra A, Barbiro B, Solomon B
J Alzheimers Dis
. 2020 Oct;
78(2):653-671.
PMID: 33016905
Background: Alzheimer's disease (AD), the prevalent dementia in the elderly, involves many related and interdependent pathologies that manifest simultaneously, leading to cognitive impairment and death. Amyloid-β (Aβ) accumulation in the...