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Asmita Sakpal

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Articles 7
Citations 64
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Mukherjee S, Sakpal A, Mehrotra M, Phadte P, Rekhi B, Ray P
Cancers (Basel) . 2022 Jul; 14(14). PMID: 35884426
An active fluidic microenvironment governs peritoneal metastasis in epithelial ovarian cancer (EOC), but its critical functional/molecular cues are not fully understood. Utilizing co-culture models of NIH3T3 cells (differentially overexpressing Jagged1)...
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Shenoy P, Chakraborty S, Gaikwad S, Sakpal A, Ray P
Bio Protoc . 2022 Mar; 12(3):e4310. PMID: 35284594
Chemoresistance, the ability of cancer cells to overcome therapeutic interventions, is an area of active research. Studies on intrinsic and acquired chemoresistance have partly succeeded in elucidating some of the...
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Bishnu A, Phadte P, Dhadve A, Sakpal A, Rekhi B, Ray P
Cell Death Dis . 2021 Feb; 12(2):161. PMID: 33558461
Alterations in key kinases and signaling pathways can fine-tune autophagic flux to promote the development of chemoresistance. Despite empirical evidences of strong association between enhanced autophagic flux with acquired chemoresistance,...
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Bishnu A, Sakpal A, Ghosh N, Choudhury P, Chaudhury K, Ray P
Int J Biochem Cell Biol . 2018 Dec; 107:116-127. PMID: 30593952
Development of resistance poses a significant challenge to effective first-line platinum based therapy for epithelial ovarian cancer patients. Cancer Stem Cells are envisaged as a critical underlying factor for therapy...
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Singh R, Dhadve A, Sakpal A, De A, Ray P
Sci Rep . 2016 Nov; 6:36612. PMID: 27819360
Deregulated IGF-1R-AKT signaling influences multiple nodes of cancer cell physiology and assists in migration, metastasis and acquirement of radio/chemoresistance. Enrichment of cancer stem cells (CSC) positively correlates with radio/chemoresistance development...
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Gaikwad S, Thakur B, Sakpal A, Singh R, Ray P
Int J Biochem Cell Biol . 2015 Feb; 61:90-102. PMID: 25681684
Development of chemoresistance is a major impediment to successful treatment of patients suffering from epithelial ovarian carcinoma (EOC). Among various molecular factors, presence of MyD88, a component of TLR-4/MyD88 mediated...