Ashwinikumar Kulkarni
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Explore the profile of Ashwinikumar Kulkarni including associated specialties, affiliations and a list of published articles.
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23
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4369
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Recent Articles
1.
Huang H, Charron T, Fu M, Dunn M, Jones D, Kumar P, et al.
bioRxiv
. 2025 Feb;
PMID: 39975408
Significance Statement: Advancing age is the single most important risk factor for neurodegenerative disease. Understanding how age intersects with genetic risk is therefore a critical challenge for neurodegenerative disease research....
2.
Vogt K, Kulkarni A, Pandi R, Pandey R, Dehnad M, Konopka G, et al.
Elife
. 2025 Feb;
13.
PMID: 39950545
Sleep loss increases AMPA-synaptic strength and number in the neocortex. However, this is only part of the synaptic sleep loss response. We report an increased AMPA/NMDA EPSC ratio in frontal-cortical...
3.
Putman J, Watson S, Zhang Z, Khandelwal N, Kulkarni A, Gibson J, et al.
J Neurosci
. 2024 Sep;
44(45).
PMID: 39317473
Experience- and activity-dependent transcription is a candidate mechanism to mediate development and refinement of specific cortical circuits. Here, we demonstrate that the activity-dependent transcription factor myocyte enhancer factor 2C (MEF2C)...
4.
Ahmed N, Khandelwal N, Anderson A, Oh E, Vollmer R, Kulkarni A, et al.
Cell Rep
. 2024 May;
43(5):114257.
PMID: 38761373
Spiny projection neurons (SPNs) of the striatum are critical in integrating neurochemical information to coordinate motor and reward-based behavior. Mutations in the regulatory transcription factors expressed in SPNs can result...
5.
Khandelwal N, Kulkarni A, Ahmed N, Harper M, Konopka G, Gibson J
Sci Adv
. 2024 May;
10(18):eadm7039.
PMID: 38701209
Long-range glutamatergic inputs originating from the cortex and thalamus are indispensable for striatal development, providing the foundation for motor and cognitive functions. Despite their significance, transcriptional regulation governing these inputs...
6.
Khandelwal N, Kulkarni A, Ahmed N, Harper M, Konopka G, Gibson J
bioRxiv
. 2023 Nov;
PMID: 37961477
Long-range glutamatergic inputs from the cortex and thalamus are critical for motor and cognitive processing in the striatum. Transcription factors that orchestrate the development of these inputs are largely unknown....
7.
Park S, Kulkarni A, Konopka G
PLoS Biol
. 2023 Aug;
21(8):e3001852.
PMID: 37540706
During cortical development, human basal radial glial cells (bRGCs) are highly capable of sustained self-renewal and neurogenesis. Selective pressures on this cell type may have contributed to the evolution of...
8.
Ahmed N, Khandelwal N, Anderson A, Kulkarni A, Gibson J, Konopka G
bioRxiv
. 2023 Jul;
PMID: 37425820
Spiny projection neurons (SPNs) of the striatum are critical in integrating neurochemical information to coordinate motor and reward-based behavior. Mutations in the regulatory transcription factors expressed in SPNs can result...
9.
Anderson A, Kulkarni A, Konopka G
Sci Rep
. 2023 Jun;
13(1):9031.
PMID: 37270616
The striatum integrates dense neuromodulatory inputs from many brain regions to coordinate complex behaviors. This integration relies on the coordinated responses from distinct striatal cell types. While previous studies have...
10.
Xu P, Berto S, Kulkarni A, Jeong B, Joseph C, Cox K, et al.
Neuron
. 2021 Aug;
109(20):3268-3282.e6.
PMID: 34416169
The suprachiasmatic nucleus (SCN) is the master circadian pacemaker in mammals and is entrained by environmental light. However, the molecular basis of the response of the SCN to light is...