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Ashwini R Madgulkar

Explore the profile of Ashwini R Madgulkar including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 78
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Recent Articles
1.
Madgulkar A, Bhalekar M, Kadam A
AAPS PharmSciTech . 2017 Jul; 19(1):293-302. PMID: 28717974
Lopinavir is a BCS Class IV drug exhibiting poor bioavailability due to P-gp efflux and limited permeation. The aim of this research was to formulate and characterize microspheres of lopinavir...
2.
Bhalekar M, Madgulkar A, Desale P, Marium G
Drug Dev Ind Pharm . 2017 Feb; 43(6):1003-1010. PMID: 28161984
The purpose of this work was to formulate piperine solid lipid nanoparticle (SLN) dispersion to exploit its efficacy orally and topically. Piperine SLN were prepared by melt emulsification method and...
3.
Bhalekar M, Upadhaya P, Madgulkar A
Eur J Pharm Sci . 2016 Jan; 84:1-8. PMID: 26776969
Rheumatoid arthritis (RA), a chronic systemic autoimmune disease, stimulates various immune cells especially macrophages, causing release of various proinflammatory cytokines such as TNF-α leading to persistent synovitis. Chloroquine, an anti-malarial...
4.
Bhalekar M, Bargaje R, Upadhaya P, Madgulkar A, Kshirsagar S
Carbohydr Polym . 2015 Nov; 136:537-42. PMID: 26572385
Tamarind seed xyloglucan is a polymer reported to possess mucoadhesive property. In the present work, role of cysteine derivative of tamarind seed polysaccharide (thiomer) to enhance the mucoadhesion and its...
5.
Madgulkar A, Bhalekar M, Padalkar R, Shaikh M
J Pharm (Cairo) . 2015 Nov; 2013:396468. PMID: 26555977
The aim was to determine the release-modifying effect of carboxymethyl xyloglucan for oral drug delivery. Sustained release matrix tablets of tramadol HCl were prepared by wet granulation method using carboxymethyl...
6.
Madgulkar A, Bhalekar M, Asgaonkar K, Dikpati A
Carbohydr Polym . 2015 Oct; 135:356-62. PMID: 26453888
A novel polymer in the form of a thiolated derivative of natural tamarind seed polysaccharide or xyloglucan was synthesized and its chacteristics as a mucoadhesive polymer were studied as a...
7.
Bansode S, Kshirsagar S, Madgulkar A, Bhalekar M, Bandivadekar M
Drug Dev Ind Pharm . 2015 Jul; 42(4):611-23. PMID: 26146768
Context: Lipoidal systems have particularly shown potential for specific accumulation in areas with inflamed tissue increasing the selectivity of local drug delivery. Objective: Formulation and evaluation of self-microemulsifying drug delivery...
8.
Bhalekar M, Upadhaya P, Madgulkar A, Kshirsagar S, Dube A, Bartakke U
Drug Deliv . 2015 May; 23(7):2581-2586. PMID: 25996834
Darunavir is effective against wild-type and PI-resistant HIV, and has an oral bioavailability of 37%. It needs to be combined with ritonavir, which increases the bioavailability to 82%. The aim...
9.
Bhalekar M, Desale S, Madgulkar A
AAPS PharmSciTech . 2010 Jul; 11(3):1171-8. PMID: 20661675
PEGylated conjugate of microcrystalline cellulose (MCC) was synthesized by reacting MCC with polyethylene glycol (PEG) 200 in the presence of catalyst at elevated temperature. Conjugation between MCC and PEG was...
10.
Madgulkar A, Bhalekar M, Kolhe V, Kenjale Y
Indian J Pharm Sci . 2010 May; 71(4):387-94. PMID: 20502544
The aim of the current study was to design sustained release matrix tablets of venlafaxine hydrochloride using ion exchange resin with the incorporation of hydrophilic and hydrophobic polymer combinations. Venlafaxine...