Ashwin Woodhoo
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Explore the profile of Ashwin Woodhoo including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
2091
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Recent Articles
1.
Martinez Garcia de la Torre R, Vallverdu J, Xu Z, Arino S, Ferrer-Lorente R, Zanatto L, et al.
Nat Commun
. 2025 Feb;
16(1):1489.
PMID: 39929812
Defining the trajectory of cells during differentiation and disease is key for uncovering the mechanisms driving cell fate and identity. However, trajectories of human cells remain largely unexplored due to...
2.
Ayuso-Garcia P, Sanchez-Rueda A, Velasco-Aviles S, Tamayo-Caro M, Ferrer-Pinos A, Huarte-Sebastian C, et al.
Sci Adv
. 2024 Apr;
10(15):eadm7600.
PMID: 38608019
Myelination is essential for neuronal function and health. In peripheral nerves, >100 causative mutations have been identified that cause Charcot-Marie-Tooth disease, a disorder that can affect myelin sheaths. Among these,...
3.
Fondevila M, Novoa E, Gonzalez-Rellan M, Fernandez U, Heras V, Porteiro B, et al.
Cell Rep Med
. 2024 Feb;
5(2):101401.
PMID: 38340725
The p63 protein has pleiotropic functions and, in the liver, participates in the progression of nonalcoholic fatty liver disease (NAFLD). However, its functions in hepatic stellate cells (HSCs) have not...
4.
Gonzalez-Rellan M, Fernandez U, Parracho T, Novoa E, Fondevila M, da Silva Lima N, et al.
Cell Metab
. 2023 Aug;
35(9):1630-1645.e5.
PMID: 37541251
Neddylation is a post-translational mechanism that adds a ubiquitin-like protein, namely neural precursor cell expressed developmentally downregulated protein 8 (NEDD8). Here, we show that neddylation in mouse liver is modulated...
5.
Capelo-Diz A, Lachiondo-Ortega S, Fernandez-Ramos D, Canas-Martin J, Goikoetxea-Usandizaga N, Serrano-Macia M, et al.
Cell Metab
. 2023 Aug;
35(8):1373-1389.e8.
PMID: 37527658
There has been an intense focus to uncover the molecular mechanisms by which fasting triggers the adaptive cellular responses in the major organs of the body. Here, we show that...
6.
Gonzalez-Cubero E, Gonzalez-Fernandez M, Rodriguez-Diaz M, Palomo-Irigoyen M, Woodhoo A, Villar-Suarez V
Front Cell Neurosci
. 2022 Sep;
16:992221.
PMID: 36159399
Background: Neuropathic pain is one of the most difficult to treat chronic pain syndromes. It has significant effects on patients' quality of life and substantially adds to the burden of...
7.
Fondevila M, Fernandez U, Heras V, Parracho T, Gonzalez-Rellan M, Novoa E, et al.
J Hepatol
. 2022 Feb;
77(1):15-28.
PMID: 35167910
Background & Aims: The pathogenesis of liver fibrosis requires activation of hepatic stellate cells (HSCs); once activated, HSCs lose intracellular fatty acids but the role of fatty acid oxidation and...
8.
Assoni G, La Pietra V, Digilio R, Ciani C, Licata N, Micaelli M, et al.
Adv Drug Deliv Rev
. 2021 Dec;
181:114088.
PMID: 34942276
The Human antigen R (HuR) protein is an RNA-binding protein, ubiquitously expressed in human tissues, that orchestrates target RNA maturation and processing both in the nucleus and in the cytoplasm....
9.
Gonzalez-Rellan M, Fondevila M, Fernandez U, Rodriguez A, Varela-Rey M, Veyrat-Durebex C, et al.
Nat Commun
. 2021 Aug;
12(1):5068.
PMID: 34417460
p53 regulates several signaling pathways to maintain the metabolic homeostasis of cells and modulates the cellular response to stress. Deficiency or excess of nutrients causes cellular metabolic stress, and we...
10.
Gonzalez-Romero F, Mestre D, Aurrekoetxea I, ORourke C, Andersen J, Woodhoo A, et al.
Cancer Res
. 2021 Mar;
81(11):2874-2887.
PMID: 33771899
Lipid metabolism rearrangements in nonalcoholic fatty liver disease (NAFLD) contribute to disease progression. NAFLD has emerged as a major risk for hepatocellular carcinoma (HCC), where metabolic reprogramming is a hallmark....