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Ashwin N Skelly

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Articles 18
Citations 1056
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Recent Articles
1.
DeLaitsch A, Keeffe J, Gristick H, Lee J, Ding W, Liu W, et al.
NPJ Vaccines . 2024 Dec; 9(1):240. PMID: 39638818
Eliciting broadly neutralizing antibodies that protect against diverse HIV-1 strains is a primary goal of AIDS vaccine research. We characterized Ab1456 and Ab1271, two heterologously-neutralizing antibodies elicited in non-human primates...
2.
Furuichi M, Kawaguchi T, Pust M, Yasuma-Mitobe K, Plichta D, Hasegawa N, et al.
Nature . 2024 Sep; 633(8031):878-886. PMID: 39294375
Persistent colonization and outgrowth of potentially pathogenic organisms in the intestine can result from long-term antibiotic use or inflammatory conditions, and may perpetuate dysregulated immunity and tissue damage. Gram-negative Enterobacteriaceae...
3.
Painter M, Johnston T, Lundgreen K, Santos J, Qin J, Goel R, et al.
Nat Immunol . 2023 Sep; 24(10):1711-1724. PMID: 37735592
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of vaccinated individuals is increasingly common but rarely results in severe disease, likely due to the enhanced potency and accelerated kinetics of...
4.
Painter M, Johnston T, Lundgreen K, Santos J, Qin J, Goel R, et al.
bioRxiv . 2023 Feb; PMID: 36798171
SARS-CoV-2 infection of vaccinated individuals is increasingly common but rarely results in severe disease, likely due to the enhanced potency and accelerated kinetics of memory immune responses. However, there have...
5.
Bibollet-Ruche F, Russell R, Ding W, Liu W, Li Y, Wagh K, et al.
mBio . 2023 Jan; 14(1):e0337022. PMID: 36629414
HIV-1 and its SIV precursors share a broadly neutralizing antibody (bNAb) epitope in variable loop 2 (V2) at the envelope glycoprotein (Env) trimer apex. Here, we tested the immunogenicity of...
6.
Ivanov I, Tuganbaev T, Skelly A, Honda K
Annu Rev Immunol . 2022 Feb; 40:559-587. PMID: 35113732
The immune system employs recognition tools to communicate with its microbial evolutionary partner. Among all the methods of microbial perception, T cells enable the widest spectrum of microbial recognition resolution,...
7.
Rando H, MacLean A, Lee A, Lordan R, Ray S, Bansal V, et al.
mSystems . 2022 Jan; 7(1):e0144721. PMID: 35076276
No abstract available.
8.
Rando H, Wellhausen N, Ghosh S, Lee A, Dattoli A, Hu F, et al.
mSystems . 2021 Nov; 6(6):e0023321. PMID: 34726496
After emerging in China in late 2019, the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread worldwide, and as of mid-2021, it remains a significant threat globally. Only...
9.
Rando H, MacLean A, Lee A, Lordan R, Ray S, Bansal V, et al.
mSystems . 2021 Oct; 6(5):e0009521. PMID: 34698547
The novel coronavirus SARS-CoV-2, which emerged in late 2019, has since spread around the world and infected hundreds of millions of people with coronavirus disease 2019 (COVID-19). While this viral...
10.
Sato Y, Atarashi K, Plichta D, Arai Y, Sasajima S, Kearney S, et al.
Nature . 2021 Jul; 599(7885):458-464. PMID: 34325466
Centenarians have a decreased susceptibility to ageing-associated illnesses, chronic inflammation and infectious diseases. Here we show that centenarians have a distinct gut microbiome that is enriched in microorganisms that are...