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Ashley M Whittington

Explore the profile of Ashley M Whittington including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Whittington A, Turner F, Baark F, Templeman S, Kirwan D, Roufosse C, et al.
PLoS Pathog . 2023 Jul; 19(7):e1011495. PMID: 37418488
Mycobacterium tuberculosis (M.tb) infection causes marked tissue inflammation leading to lung destruction and morbidity. The inflammatory extracellular microenvironment is acidic, however the effect of this acidosis on the immune response...
2.
Barnacle J, Chow Y, Borman A, Wyllie S, Dominguez V, Russell K, et al.
Med Mycol Case Rep . 2023 Jan; 39:14-17. PMID: 36590368
An epidemic of cat-transmitted sporotrichosis caused by has emerged as a major public health threat in Brazil in recent decades. We report the first three cases of cat-transmitted sporotrichosis caused...
3.
Fox K, Kirwan D, Whittington A, Krishnan N, Robertson B, Gilman R, et al.
Am J Respir Crit Care Med . 2018 Feb; 198(2):245-255. PMID: 29420060
Rationale: Platelets may interact with the immune system in tuberculosis (TB) to regulate human inflammatory responses that lead to morbidity and spread of infection. Objectives: To identify a functional role...
4.
Brilha S, Wysoczanski R, Whittington A, Friedland J, Porter J
J Immunol . 2017 Jun; 199(3):982-991. PMID: 28646039
In tuberculosis (TB), the innate inflammatory immune response drives tissue destruction, morbidity, and mortality. Monocytes secrete matrix metalloproteinases (MMPs), which have key roles in local tissue destruction and cavitation. We...
5.
Barr D, Whittington A, White B, Patterson B, Davidson R
J Infect . 2012 Sep; 66(4):313-9. PMID: 22935576
We describe five individuals in whom extra-pulmonary tuberculosis appeared to localise at a site of previous blunt injury. We review other similar case reports where preceding trauma was blunt and...