Ashley F George
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Explore the profile of Ashley F George including associated specialties, affiliations and a list of published articles.
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20
Citations
434
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Recent Articles
1.
George A, Neidleman J, Luo X, Frouard J, Elphick N, Yin K, et al.
Cell Rep
. 2025 Jan;
44(1):115202.
PMID: 39798087
We developed viral sensor and restriction factor-cytometry by time of flight (VISOR-CyTOF), which profiles 19 viral sensors and restriction factors (VISORs) simultaneously in single cells, and applied it to 41...
2.
George A, Roan N
Curr HIV/AIDS Rep
. 2023 Jan;
20(2):76-85.
PMID: 36689119
Purpose Of Review: This review describes how advances in CyTOF and high-dimensional analysis methods have furthered our understanding of HIV transmission, pathogenesis, persistence, and immunity. Recent Findings: CyTOF has generated...
3.
George A, McGregor M, Gingrich D, Neidleman J, Marquez R, Young K, et al.
Viruses
. 2022 Aug;
14(8).
PMID: 36016345
The efficacy of HIV pre-exposure prophylaxis (PrEP) is high in men who have sex with men, but much more variable in women, in a manner largely attributed to low adherence....
4.
Ma T, McGregor M, Giron L, Xie G, George A, Abdel-Mohsen M, et al.
Elife
. 2022 Jul;
11.
PMID: 35787792
High-parameter single-cell phenotyping has enabled in-depth classification and interrogation of immune cells, but to date has not allowed for glycan characterization. Here, we develop CyTOF-Lec as an approach to simultaneously...
5.
Suryawanshi R, Chen I, Ma T, Syed A, Brazer N, Saldhi P, et al.
Nature
. 2022 May;
607(7918):351-355.
PMID: 35584773
SARS-CoV-2 Delta and Omicron are globally relevant variants of concern. Although individuals infected with Delta are at risk of developing severe lung disease, infection with Omicron often causes milder symptoms,...
6.
Vallve-Juanico J, George A, Sen S, Thomas R, Shin M, Kushnoor D, et al.
BMC Med
. 2022 Apr;
20(1):158.
PMID: 35421980
Background: Endometriosis is a chronic, estrogen-dependent disorder where inflammation contributes to disease-associated symptoms of pelvic pain and infertility. Immune dysfunction includes insufficient immune lesion clearance, a pro-inflammatory endometrial environment, and...
7.
George A, Luo X, Neidleman J, Hoh R, Vohra P, Thomas R, et al.
Front Immunol
. 2022 Feb;
13:803417.
PMID: 35154118
T and natural killer (NK) cells are effector cells with key roles in anti-HIV immunity, including in lymphoid tissues, the major site of HIV persistence. However, little is known about...
8.
Suryawanshi R, Chen I, Ma T, Syed A, Brazer N, Saldhi P, et al.
medRxiv
. 2022 Jan;
PMID: 35075459
SARS-CoV-2 Delta and Omicron strains are the most globally relevant variants of concern (VOCs). While individuals infected with Delta are at risk to develop severe lung disease , Omicron infection...
9.
Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells
Adeniji O, Kuri-Cervantes L, Yu C, Xu Z, Ho M, Chew G, et al.
PLoS Pathog
. 2021 Nov;
17(11):e1010034.
PMID: 34762717
Siglec-9 is an MHC-independent inhibitory receptor expressed on a subset of natural killer (NK) cells. Siglec-9 restrains NK cytotoxicity by binding to sialoglycans (sialic acid-containing glycans) on target cells. Despite...
10.
Ma T, Ryu H, McGregor M, Babcock B, Neidleman J, Xie G, et al.
J Immunol
. 2021 Aug;
207(5):1344-1356.
PMID: 34389625
CD8 T cells can potentiate long-lived immunity against COVID-19. We screened longitudinally-sampled convalescent human donors against SARS-CoV-2 tetramers and identified a participant with an immunodominant response against residues 322 to...