Ashley C Brown
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Explore the profile of Ashley C Brown including associated specialties, affiliations and a list of published articles.
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83
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1081
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Recent Articles
1.
Young A, Deal H, Rusch G, Pozdin V, Brown A, Daniele M
Organs Chip
. 2025 Feb;
5.
PMID: 39949484
Microphysiological systems (MPS) incorporate physiologically relevant microanatomy, mechanics, and cells to mimic tissue function. Reproducible and standardized models of tissue barriers, such as the blood-tissue interface (BTI), are critical for...
2.
Deal H, Byrnes E, Pandit S, Sheridan A, Brown A, Daniele M
Lab Chip
. 2025 Jan;
25(3):440-453.
PMID: 39763291
Blood coagulation is a highly regulated injury response that features polymerization of fibrin fibers to prevent the passage of blood from a damaged vascular endothelium. A growing body of research...
3.
Pozy E, Brown A
J Thromb Haemost
. 2024 Dec;
23(3):790-803.
PMID: 39675569
Bleeding is a leading cause of trauma deaths and surgical complications. Excessive bleeding has traditionally been treated with the transfusion of donated blood. However, the complicated logistics of sourcing and...
4.
Palomino T, Sheridan A, Muddiman D, Brown A
Res Pract Thromb Haemost
. 2024 Dec;
8(8):102618.
PMID: 39668886
Background: Fetal fibrinogen is a variant present in neonates. Blood products used in neonates are tailored for adults and do not seamlessly integrate into neonatal clots. Increased sialic acid content...
5.
Oshinowo O, Copeland R, Patel A, Shaver N, Fay M, Jeltuhin R, et al.
Nat Commun
. 2024 Nov;
15(1):10201.
PMID: 39587073
Altered mechanotransduction has been proposed as a putative mechanism for disease pathophysiology, yet evidence remains scarce. Here we introduce a concept we call single cell immuno-mechanical modulation, which links immunology,...
6.
Ward C, Curry N, El-Ekiaby M, Jurk K, Versteeg H, Keragala C, et al.
Res Pract Thromb Haemost
. 2024 Sep;
8(5):102498.
PMID: 39268352
[This corrects the article DOI: 10.1016/j.rpth.2024.102432.].
7.
Ozawa S, Pierce K, Thomson A, Moiseiwitsch N, Stephens J, LeGrand J, et al.
J Am Assoc Lab Anim Sci
. 2024 Sep;
63(6):669-674.
PMID: 39231618
Cardiac troponin I (cTnI) is a cardiac-specific biomarker, used for the detection of myocardial injury. While rabbits develop naturally occurring cardiovascular disease, they are also an animal model for human...
8.
Downey L, Moiseiwitsch N, Nellenbach K, Xiang Y, Brown A, Guzzetta N
Anesth Analg
. 2024 Aug;
PMID: 39116012
Background: Neonates undergoing cardiac surgery require fibrinogen replacement to restore hemostasis after cardiopulmonary bypass (CPB). Cryoprecipitate is often the first-line treatment, but recent studies demonstrate that fibrinogen concentrate (RiaSTAP; CSL...
9.
Wang Z, Mahmood N, Budhathoki-Uprety J, Brown A, King M, Gluck J
ACS Appl Bio Mater
. 2024 Jul;
7(8):5519-5529.
PMID: 39037196
In this study, we report on the preparation, characterization, and cytocompatibility of hydrogels for biomedical applications made from two different molecular weights of chitosan (CS) blended with poly(vinyl alcohol) (PVA)...
10.
Simpson A, Mihalko E, Fox C, Sridharan S, Krishnakumar M, Brown A
Matrix Biol Plus
. 2024 Jun;
23:100150.
PMID: 38882395
Cardiac fibrosis is characterized by excessive accumulation and deposition of ECM proteins. Cardiac fibrosis is commonly implicated in a variety of cardiovascular diseases, including post-myocardial infarction (MI). We have previously...