Asher Maroof
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Explore the profile of Asher Maroof including associated specialties, affiliations and a list of published articles.
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34
Citations
1129
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Recent Articles
1.
Qureshi O, Sutton E, Bithell R, West S, Cutler R, McCluskey G, et al.
MAbs
. 2024 Jan;
16(1):2300155.
PMID: 38241085
Rozanolixizumab is a humanized anti-neonatal Fc receptor (FcRn) monoclonal antibody (mAb) of the immunoglobulin G4 (IgG4) sub-class, currently in clinical development for the treatment of IgG autoantibody-driven diseases. This format...
2.
Cole S, Manghera A, Burns L, Barrett J, Yager N, Rhys H, et al.
J Allergy Clin Immunol
. 2023 May;
152(3):783-798.
PMID: 37244461
Background: IL-17A plays a pivotal pathogenic role in several immune-mediated inflammatory diseases. Despite sharing 50% sequence homology with IL-17A, the role of IL-17F remains less clear. Clinical findings suggest that...
3.
Dave E, Durrant O, Dhami N, Compson J, Broadbridge J, Archer S, et al.
MAbs
. 2023 Feb;
15(1):2160229.
PMID: 36788124
TrYbe® is an Fc-free therapeutic antibody format, capable of engaging up to three targets simultaneously, with long half-life conferred by albumin binding. This format is shown by small-angle X-ray scattering...
4.
Cole S, Murray J, Simpson C, Okoye R, Tyson K, Griffiths M, et al.
Front Immunol
. 2020 Dec;
11:585134.
PMID: 33329560
IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for inducing IL-17 production in other human immune subsets remains incompletely understood. Mucosal associated invariant T...
5.
Adams R, Maroof A, Baker T, Lawson A, Oliver R, Paveley R, et al.
Front Immunol
. 2020 Sep;
11:1894.
PMID: 32973785
Interleukin (IL)-17A is a key driver of inflammation and the principal target of anti-IL-17 therapeutic monoclonal antibodies. IL-17A, and its structurally similar family member IL-17F, have been shown to be...
6.
Shah M, Maroof A, Gikas P, Mittal G, Keen R, Baeten D, et al.
RMD Open
. 2020 Jul;
6(2).
PMID: 32723833
Objectives: Interleukin (IL)-17 signalling has been shown to be a key regulator of disease in ankylosing spondylitis (AS) with several IL-17 blockers currently clinically approved. Despite this, the role of...
7.
Hayes A, Rane S, Scales H, Meehan G, Benson R, Maroof A, et al.
Front Immunol
. 2019 Apr;
10:598.
PMID: 31024523
Initiation of adaptive immunity involves distinct migratory cell populations coming together in a highly dynamic and spatially organized process. However, we lack a detailed spatiotemporal map of these events due...
8.
Maroof A, Patel D
J Allergy Clin Immunol
. 2018 Jun;
142(2):401-402.
PMID: 29859964
No abstract available.
9.
Moore J, Beattie L, Osman M, Owens B, Brown N, Dalton J, et al.
PLoS One
. 2016 Sep;
11(9):e0163604.
PMID: 27658046
Recent thymic emigrants (RTEs) represent a source of antigen-naïve T cells that enter the periphery throughout life. However, whether RTEs contribute to the control of chronic parasitic infection and how...
10.
Maroof A, Yorgensen Y, Li Y, Evans J
PLoS Pathog
. 2014 Jan;
10(1):e1003875.
PMID: 24465206
Influenza disease is a global health issue that causes significant morbidity and mortality through seasonal epidemics. Currently, inactivated influenza virus vaccines given intramuscularly or live attenuated influenza virus vaccines administered...