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Arya Mani

Explore the profile of Arya Mani including associated specialties, affiliations and a list of published articles. Areas
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Articles 77
Citations 1681
Followers 0
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Recent Articles
1.
Lee J, Mani A, Shin M, Krauss R
Prog Lipid Res . 2024 Jul; 95:101288. PMID: 38964473
B cell malignancies, comprising over 80 heterogeneous blood cancers, pose significant prognostic challenges due to intricate oncogenic signaling. Emerging evidence emphasizes the pivotal role of disrupted lipid metabolism in the...
2.
Tanaka K, Chen M, Prendergast A, Zhuang Z, Nasiri A, Joshi D, et al.
bioRxiv . 2024 Jun; PMID: 38915515
Endothelial cell responses to fluid shear stress from blood flow are crucial for vascular development, function and disease. A complex of PECAM-1, VE-cadherin, VEGF receptors (VEGFRs) and PlexinD1 located at...
3.
Tanaka K, Chen M, Prendergast A, Zhuang Z, Nasiri A, Joshi D, et al.
EMBO J . 2024 Jun; 43(15):3175-3191. PMID: 38886581
Endothelial cell responses to fluid shear stress from blood flow are crucial for vascular development, function, and disease. A complex of PECAM-1, VE-cadherin, VEGF receptors (VEGFRs), and Plexin D1 located...
4.
Jiang Q, Song G, He L, Li X, Jiang B, Wang Q, et al.
Kidney Int . 2024 May; 106(3):419-432. PMID: 38797325
ZFYVE21 is an ancient, endosome-associated protein that is highly expressed in endothelial cells (ECs) but whose function(s) in vivo are undefined. Here, we identified ZFYVE21 as an essential regulator of...
5.
Mani A
Cell Mol Life Sci . 2024 May; 81(1):201. PMID: 38691164
Hypertension is a heritable disease that affects one-fourth of the population and accounts for about 50% of cardiovascular deaths. The genetic basis of hypertension is multifaceted, involving both monogenic and...
6.
Kim T, DeWan A, Murray M, Wang H, Mani A, Mena-Hurtado C, et al.
Ann Vasc Surg . 2024 Apr; 105:150-157. PMID: 38593922
Background: Premature peripheral artery disease (PAD), defined by lower extremity revascularization (LER) at age ≤ 50 years, is associated with poor major adverse limb events. The early onset of disease...
7.
Mani A
Elife . 2023 Dec; 12. PMID: 38060304
A deep analysis of multiple genomic datasets reveals which genetic pathways associated with atherosclerosis and coronary artery disease are shared between mice and humans.
8.
Anushiravani A, Jafari Khamirani H, Mohamadkhani A, Mani A, Dianatpour M, Malekzadeh R
Arch Iran Med . 2023 Aug; 26(2):86-91. PMID: 37543928
Background: The LIPA gene on chromosome 10q23.31 contains 10 exons and encodes lipase A, the lysosomal acid lipase (LAL) containing 399 amino acids. Pathogenic variants in the LIPA result in...
9.
Masoudkabir F, Mohammadifard N, Mani A, Ignaszewski A, Davis M, Vaseghi G, et al.
ScientificWorldJournal . 2023 Jul; 2023:2404806. PMID: 37520844
Cardiovascular disease (CVD) and cancer are leading causes of mortality and morbidity worldwide and are the major focus of the World Health Organization's joint prevention programs. While, diverse diseases, CVD...
10.
Wiegand A, Kastury R, Neogi A, Mani A, Bale A, Cox A
Cold Spring Harb Mol Case Stud . 2023 Jul; 9(3). PMID: 37433679
Hereditary connective tissue disorders have overlapping phenotypes, particularly in regard to musculoskeletal features. This contributes to the challenge of phenotype-based clinical diagnoses. However, some hereditary connective tissue disorders have distinct...