Arunachalam Muthuraman
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Explore the profile of Arunachalam Muthuraman including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Muthuraman A, Sayem A, Meenakshisundaram S, Ali N, Ahmad S, Alasmari A, et al.
Biomedicines
. 2023 Oct;
11(10).
PMID: 37893028
Indoxyl sulfate (IS) is a metabolic byproduct of indole metabolism. IS readily interacts with the mitochondrial redox metabolism, leading to altered renal function. The β-carotene oxygenase-2 (BCO2) enzyme converts carotenoids...
2.
Paramakrishnan N, Lim K, Paramaswaran Y, Ali N, Waseem M, Shazly G, et al.
Mar Drugs
. 2023 Aug;
21(8).
PMID: 37623714
Alzheimer's disease (AD) is a major type of dementia disorder. Common cognitive changes occur as a result of cerebrovascular damage (CVD) via the disruption of matrix metalloproteinase-13 (MMP-13). In diabetic...
3.
Shaikh S, Muthuraman A
Pharmaceuticals (Basel)
. 2023 Jun;
16(6).
PMID: 37375775
Neurovascular dysfunction leads to the second most common type of dementia, i.e., vascular dementia (VaD). Toxic metals, such as aluminium, increase the risk of neurovascular dysfunction-associated VaD. Hence, we hypothesized...
4.
Muthuraman A, Ramesh M, Mustaffa F, Nadeem A, Nishat S, Paramakrishnan N, et al.
Molecules
. 2023 Jun;
28(11).
PMID: 37298835
Molecular docking is widely used in the assessment of the therapeutic potential of pharmaceutical agents. The binding properties of beta-carotene (BC) to acetylcholine esterase (AChE) proteins were characterized using the...
5.
Paramakrishnan N, Chavan L, Lim K, Paramaswaran Y, Muthuraman A
Pharmaceuticals (Basel)
. 2023 Jun;
16(2).
PMID: 37259308
Beta carotene is a natural anti-oxidant agent, and it inhibits the matrix metalloprotease (MMP) activity. Diabetic neuropathic pain (DNP) is produced by cellular oxidative stress. The role of the beta...
6.
Paramaswaran Y, Subramanian A, Paramakrishnan N, Ramesh M, Muthuraman A
Pharmaceuticals (Basel)
. 2023 May;
16(5).
PMID: 37242430
Diabetic retinopathy (DR) primarily progresses into retinal degeneration caused by microvascular dysfunction. The pathophysiology of DR progression is still uncertain. This study investigates the function of beta-carotene (PBC) originating from...
7.
Shaikh S, Varatharajan R, Muthuraman A
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36362316
Vascular dementia (VaD) is a serious global health issue and type 2 diabetes mellitus (T2DM) patients are at higher risk. Palm oil tocotrienol-rich fraction (TRF) exhibits neuroprotective properties; however, its...
8.
Dhamodharan J, Sekhar G, Muthuraman A
Molecules
. 2022 Aug;
27(16).
PMID: 36014421
Alzheimer's disease (AD) is one of the major neurodegenerative disorders, and its incidence increases globally every year. Currently, available AD drugs symptomatically treat AD with multiple adverse effects. Gefitinib (GE)...
9.
Lim K, Varatharajan R, Muthuraman A
Molecules
. 2022 Jul;
27(13).
PMID: 35807538
This study investigated the ameliorative effects of beta-carotene (BC) on diabetes-associated vascular dementia and its action against biomolecule oxidation. The diabetic vascular dementia (VaD) was induced by administration of nicotinamide...
10.
Muthuraman A, Ramesh M, Shaikh S, Aswinprakash S, Jagadeesh D
Drug Metab Lett
. 2021 Dec;
14(3):177-192.
PMID: 34895129
Cysteine is one of the major intermediate products of cellular amino-acid metabolism. It is a semi-essential amino acid for protein synthesis. Besides, it is also employed in the regulation of...