Arun M Dharmarajan
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Explore the profile of Arun M Dharmarajan including associated specialties, affiliations and a list of published articles.
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25
Citations
349
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Recent Articles
1.
Perumal V, Corica T, Dharmarajan A, Sun Z, Dhaliwal S, Dass C, et al.
Cancers (Basel)
. 2019 Mar;
11(3).
PMID: 30875950
Head and neck cancer is the seventh most common cancer in Australia and globally. Despite the current improved treatment modalities, there is still up to 50⁻60% local regional recurrence and...
2.
Carnagarin R, Elahy M, Dharmarajan A, Dass C
Mol Cell Endocrinol
. 2017 Dec;
472:159-166.
PMID: 29258756
Extensive bone defects arising as a result of trauma, infection and tumour resection and other bone pathologies necessitates the identification of effective strategies in the form of tissue engineering, gene...
3.
Perumal V, Arfuso F, Chen Y, Fox S, Dharmarajan A
Mol Cell Biochem
. 2017 Nov;
443(1-2):205-213.
PMID: 29185158
In malignant mesothelioma (MM) cells, secreted frizzled-related protein 4 (SFRP4) expression is downregulated by promoter methylation. In this study, we evaluated the effect of encapsulated chitosan-dextran (CS-DS) nanoparticle formulations of...
4.
Perumal V, Dharmarajan A, Fox S
Int J Oncol
. 2017 May;
51(1):362-368.
PMID: 28534940
Secreted frizzled related proteins (SFRPs) are a family of Wnt regulators which are frequently downregulated in cancers. In malignant mesothelioma (MM), downregulation of SFRP4 has been reported as a mechanism...
5.
Saran U, Mani K, Balaguru U, Swaminathan A, Nagarajan S, Dharmarajan A, et al.
Nitric Oxide
. 2017 Mar;
66:30-42.
PMID: 28267592
Nitric oxide (NO) plays a critical role in endothelial functions such as cellular migration, vascular permeability and angiogenesis. Angiogenesis, the formation of new blood vessels from "pre-existing" ones is a...
6.
Carnagarin R, Carlessi R, Newsholme P, Dharmarajan A, Dass C
Int J Biochem Cell Biol
. 2016 Jun;
78:229-236.
PMID: 27343430
Pigment epithelium-derived factor is a multifunctional serpin implicated in insulin resistance in metabolic disorders. Recent evidence suggests that exposure of peripheral tissues such as skeletal muscle to PEDF has profound...
7.
Carnagarin R, Dharmarajan A, Dass C
Mol Cell Endocrinol
. 2015 Dec;
422:115-124.
PMID: 26700654
Pigment epithelium-derived factor (PEDF) is an anti-angiogenic serpin associated with insulin resistance in metabolic disorders such as diabetes, metabolic syndrome, obesity and polycystic ovarian syndrome. While the mechanism of PEDF...
8.
Carnagarin R, Dharmarajan A, Dass C
Mol Cell Endocrinol
. 2015 Sep;
417:52-62.
PMID: 26362689
Among all the varied actions of insulin, regulation of glucose homeostasis is the most critical and intensively studied. With the availability of glucose from nutrient metabolism, insulin action in muscle...
9.
Perumal V, Krishnan K, Gratton E, Dharmarajan A, Fox S
Int J Biochem Cell Biol
. 2015 Mar;
64:91-6.
PMID: 25805505
The Wnts are secreted, lipidated glycoproteins that play a role in cellular processes of differentiation, proliferation, migration, survival, polarity and stem cell self-renewal. The majority of Wnts biological effects are...
10.
Goh J, Loo S, Datta A, Siveen K, Yap W, Cai W, et al.
Biol Rev Camb Philos Soc
. 2015 Jan;
91(2):409-28.
PMID: 25631495
A large number of etiological factors and the complexity of breast cancers present challenges for prevention and treatment. Recently, the emergence of microRNAs (miRNAs) as cancer biomarkers has added an...