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Arun Dharmarajan

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Articles 71
Citations 1194
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Recent Articles
11.
Yasmin I, Dharmarajan A, Warrier S
Cancers (Basel) . 2023 Jul; 15(14). PMID: 37509281
Growing evidence indicates that cancer stem cells (CSCs) endow the tumor with stem-like properties. Recently, induced pluripotent stem cells (iPSCs) have gained increased attention because of their easy derivation and...
12.
Soumya B, Shreenidhi V, Agarwal A, Gandhirajan R, Dharmarajan A, Warrier S
Cell Signal . 2023 Jul; 110:110807. PMID: 37463628
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative condition, triggered by various factors causing the degeneration of upper and lower motor neurons, resulting in progressive muscle wasting, paralysis, and death....
13.
Brook N, Dharmarajan A, Chan A, Dass C
J Pharm Pharmacol . 2023 Apr; 75(7):873-885. PMID: 37116213
Objectives: This review discusses key oestrogens associated with the circulating pre- and post-menopausal milieu and how they may impact intratumoral oestrogen levels and breast cancer (BC) metastasis. It also identifies...
14.
Murali R, Balasubramaniam V, Srinivas S, Sundaram S, Venkatraman G, Warrier S, et al.
Metabolites . 2023 Apr; 13(4). PMID: 37110218
Ovarian cancers are tumors that originate from the different cells of the ovary and account for almost 4% of all the cancers in women globally. More than 30 types of...
15.
Gamit N, Dharmarajan A, Sethi G, Warrier S
Biochem Pharmacol . 2023 Apr; 212:115566. PMID: 37088155
Nuclear receptor related 1 (Nurr1) is a transcription factor known to regulate the development and maintenance of midbrain dopaminergic (mDA) neurons. Reports have confirmed that defect or obliteration of Nurr1...
16.
Patil M, Gamit N, Dharmarajan A, Sethi G, Warrier S
Bioengineering (Basel) . 2023 Feb; 10(2). PMID: 36829686
Currently, all the existing treatments for Alzheimer's disease (AD) fail to stall progression due to longer duration of time between onset of the symptoms and diagnosis of the disease, raising...
17.
Sundaram S, Varier L, Fathima K, Dharmarajan A, Warrier S
Life Sci . 2023 Jan; 316:121384. PMID: 36646377
Aims: One of the hallmarks of cancer stem cells (CSC) is hyperactive Wnt β-catenin signaling due to the decreased presence of Wnt antagonists such as secreted frizzled related protein 4...
18.
Brook N, Gill J, Dharmarajan A, Chan A, Dass C
Int J Mol Sci . 2022 Dec; 23(24). PMID: 36555293
Pigment epithelium-derived factor (PEDF) protein regulates normal bone, with anti-tumour roles in bone and breast cancer (BC). Pre- and post-menopausal oestrogen levels may regulate PEDF expression and function in BC,...
19.
Brook N, Gill J, Chih H, Francis K, Dharmarajan A, Chan A, et al.
Mol Cell Endocrinol . 2022 Oct; 559:111792. PMID: 36309204
Pigment epithelium-derived factor (PEDF) has a critical role in bone development and anti-tumour function in breast cancer (BC). As the expression and role of PEDF in BC bone metastases is...
20.
Ganesh J, P P, Dharmarajan A, Warrier S, Gandhirajan R
Free Radic Res . 2022 Oct; 56(5-6):447-470. PMID: 36214686
Oxidation-reduction reactions played a significant role in the chemical evolution of life forms on oxygenated earth. Cellular respiration is dependent on such redox reactions, and any imbalance leads to the...