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Arturo Benitez

Explore the profile of Arturo Benitez including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 8
Citations 44
Followers 0
Related Specialties
Neurology
Psychology
Social Sciences
Top 10 Co-Authors
Mahnaz Asgharnejad
J Scott Andrews
Drishti Shah
Jeannine Roth
Martha Fournier
Mei Lu
Aimee Jones
William Spalding
Emma Butcher
J Helen Cross
Published In
Epilepsia
Epilepsy Behav
Ann N Y Acad Sci
Heliyon
Postgrad Med
Affiliations
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Recent Articles
1.
Development and refinement of the Clinical Global Impression of Improvement for Non-seizure Symptoms measure in Dravet syndrome and Lennox-Gastaut syndrome
Scott Andrews J, Shah D, Nacson A, Symonds T, Hughes S, Asgharnejad M, et al.
J Patient Rep Outcomes . 2025 Feb; 9(1):24. PMID: 39982628
Background: Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS) are rare, severe, childhood-onset developmental and epileptic encephalopathies characterized by treatment-resistant epilepsy and varying intellectual disability levels. Clinical outcome assessments (COAs) describe...
2.
A review of the putative antiseizure and antiepileptogenic mechanisms of action for soticlestat
Kondo S, Murthy V, Asgharnejad M, Benitez A, Nakashima K, Hawkins N, et al.
Epilepsia . 2025 Feb; PMID: 39963730
Soticlestat (TAK-935) is a potent and selective inhibitor of cholesterol 24-hydroxylase (CYP46A1), an enzyme primarily expressed in the brain that catabolizes cholesterol to 24S-hydroxycholesterol (24HC). In the ELEKTRA phase II...
3.
Development of cohort definitions and algorithms to identify patients with Lennox-Gastaut syndrome or Dravet syndrome from real-world administrative healthcare databases
Shah D, Divino V, Chen J, Benitez A, Roth J, Scott Andrews J
Heliyon . 2025 Feb; 11(3):e41486. PMID: 39959501
Objective: To develop cohort definitions and algorithms that can be applied to a range of real-world retrospective data sources in the United States, France, Germany, Italy, Spain, United Kingdom, China,...
4.
A comprehensive systematic literature review of the burden of illness of Lennox-Gastaut syndrome on patients, caregivers, and society
Cross J, Benitez A, Roth J, Scott Andrews J, Shah D, Butcher E, et al.
Epilepsia . 2024 Mar; 65(5):1224-1239. PMID: 38456647
Fully elucidating the burden that Lennox-Gastaut syndrome (LGS) places on individuals with the disease and their caregivers is critical to improving outcomes and quality of life (QoL). This systematic literature...
5.
A systematic literature review on the global epidemiology of Dravet syndrome and Lennox-Gastaut syndrome: Prevalence, incidence, diagnosis, and mortality
Sullivan J, Benitez A, Roth J, Scott Andrews J, Shah D, Butcher E, et al.
Epilepsia . 2024 Jan; 65(5):1240-1263. PMID: 38252068
Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS) are rare developmental and epileptic encephalopathies associated with seizure and nonseizure symptoms. A comprehensive understanding of how many individuals are affected globally, the...
6.
A Phase 3 open-label study of the efficacy, safety and pharmacokinetics of buccally administered midazolam hydrochloride for the treatment of status epilepticus in pediatric Japanese subjects
Yoshinaga H, Benitez A, Takeda S, Fournier M, Kugler A
Epilepsy Res . 2021 May; 174:106651. PMID: 34020149
Background: In Japan, intravenous (IV) administration of antiepileptic drugs in a healthcare setting is the preferred treatment option that is both licensed and recommended for initial treatment of status epilepticus...
7.
Epidemiology of status epilepticus in the United States: A systematic review
Lu M, Faure M, Bergamasco A, Spalding W, Benitez A, Moride Y, et al.
Epilepsy Behav . 2020 Nov; 112:107459. PMID: 33181886
Objectives: Convulsive status epilepticus (CSE) is a life-threatening neurologic emergency, which is defined by the International League Against Epilepsy (ILAE) as bilateral tonic-clonic seizure activity lasting longer than 5 min,...
8.
Burden of disease in patients with a history of status epilepticus and their caregivers
King-Stephens D, Wheless J, Krogh C, Bettles M, Niemira J, Stolper R, et al.
Epilepsy Behav . 2020 Sep; 112:107374. PMID: 32882626
Objective: Status epilepticus (SE) is a life-threatening neurological emergency with the potential for wide-ranging impact on patients and caregivers. In this study, the burden of disease in patients with a...
9.
Switching from an oral dopamine receptor agonist to rotigotine transdermal patch: a review of clinical data with a focus on patient perspective
Chung S, Asgharnejad M, Bauer L, Benitez A, Boroojerdi B, Heidbrede T, et al.
Expert Rev Neurother . 2017 May; 17(7):737-749. PMID: 28548894
Dopamine receptor agonists (DAs) are commonly used to treat Parkinson's disease (PD) and restless legs syndrome (RLS). In certain situations, switching from oral DAs to rotigotine transdermal patch may be...
10.
Augmentation of restless leg syndrome (Willis-Ekbom disease) during long-term dopaminergic treatment
Garcia-Borreguero D, Benitez A, Kohnen R, Allen R
Postgrad Med . 2015 Jun; 127(7):716-25. PMID: 26077324
Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is a common sensorimotor disorder that can generally be effectively managed in the primary care clinic. However, some treatment complications...