Arto Orpana
Overview
Explore the profile of Arto Orpana including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
164
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Litonius K, Kulla N, Falkenbach P, Kristiansson K, Tarkiainen E, Ukkola-Vuoti L, et al.
Clin Pharmacol Ther
. 2024 Oct;
117(1):278-288.
PMID: 39365028
Implementation of pharmacogenetic testing in clinical care has been slow and with few exceptions is hindered by the lack of real-world evidence on how to best target testing. In this...
2.
Kiiski J, Neuvonen M, Kurkela M, Hirvensalo P, Hamalainen K, Tarkiainen E, et al.
Hum Genomics
. 2024 Feb;
18(1):11.
PMID: 38303026
Background: Individual assessment of CYP enzyme activities can be challenging. Recently, the potato alkaloid solanidine was suggested as a biomarker for CYP2D6 activity. Here, we aimed to characterize the sensitivity...
3.
Tran T, Dang K, Pham Q, Nguyen U, Trinh N, Hoang L, et al.
BMC Cancer
. 2020 May;
20(1):368.
PMID: 32357861
Background: The BRAF gene encodes for the mutant BRAF protein, which triggers downstream oncogenic signaling in thyroid cancer. Since most currently available methods have focused on detecting BRAF mutations in...
4.
Helin T, Joutsi-Korhonen L, Asmundela H, Niemi M, Orpana A, Lassila R
Br J Clin Pharmacol
. 2019 Apr;
85(8):1684-1691.
PMID: 30933373
Aims: Warfarin dose requirement varies significantly. We compared the clinically established doses based on international normalized ratio (INR) among patients with severe thrombosis and/or thrombophilia with estimates from genetic dosing...
5.
Dang K, Ho T, Sistonen S, Koivusalo A, Pakarinen M, Rintala R, et al.
Eur J Pediatr Surg
. 2017 Sep;
28(5):413-419.
PMID: 28873491
Background: Previous studies have reported an association among esophageal atresia (EA), Barrett's esophagus, and esophageal adenocarcinoma later in life. Objective: The objective of the article is to evaluate KRAS and...
6.
Algars A, Sundstrom J, Lintunen M, Jokilehto T, Kytola S, Kaare M, et al.
Int J Cancer
. 2016 Nov;
140(4):922-929.
PMID: 27879995
Anti-EGFR antibodies are used for the treatment of RAS wild type metastatic colorectal cancer. We previously showed that EGFR gene copy number (GCN) predicts response to anti-EGFR therapy in KRAS...
7.
Thiel A, Moza M, Kytola S, Orpana A, Jahkola T, Hernberg M, et al.
Hum Pathol
. 2014 Dec;
46(2):169-75.
PMID: 25442222
The v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600E mutation is the most common activating genetic alteration of this oncogene and a predictive marker for the therapeutic use of...
8.
Thiel A, Heinonen M, Kantonen J, Gylling A, Lahtinen L, Korhonen M, et al.
Virchows Arch
. 2013 Aug;
463(5):613-21.
PMID: 23963522
The aim of the study was to detect mutations of BRAF oncogene in colorectal cancer and to use this information to identify Lynch syndrome patients. Consecutive cases of primary colorectal...
9.
Feng L, Lintula S, Ho T, Anastasina M, Paju A, Haglund C, et al.
Biotechniques
. 2012 Apr;
52(4):263-70.
PMID: 22482442
Primer-independent cDNA synthesis during reverse transcription hinders quantitative analysis of bidirectional mRNA synthesis in eukaryotes as well as in cells infected with RNA viruses. We report a simple RT-PCR-based assay...
10.
Fang S, Repo H, Joensuu H, Orpana A, Salven P
Eur J Cancer
. 2011 Mar;
47(11):1708-16.
PMID: 21439815
Background: Angiogenin is a potent inducer of angiogenesis. We prospectively evaluated the prognostic significance of serum angiogenin from 204 consecutive non-Hodgkin lymphoma (NHL) patients diagnosed and treated in a single...