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Artem S Silchenko

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Articles 26
Citations 256
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Recent Articles
1.
Silchenko A, Taran I, Usoltseva R, Zvyagintsev N, Zueva A, Rubtsov N, et al.
Int J Mol Sci . 2024 Jan; 25(1). PMID: 38203394
Sulfated polysaccharides of brown algae, fucoidans, are known for their anticoagulant properties, similar to animal heparin. Their complex and irregular structure is the main bottleneck in standardization and in defining...
2.
Malyarenko O, Usoltseva R, Silchenko A, Zueva A, Ermakova S
Int J Mol Sci . 2023 Aug; 24(15). PMID: 37569428
Melanoma is the most aggressive and treatment-resistant form of skin cancer. It is phenotypically characterized by aerobic glycolysis that provides higher proliferative rates and resistance to cell death. The glycolysis...
3.
Zueva A, Silchenko A, Rasin A, Malyarenko O, Kusaykin M, Kalinovsky A, et al.
Carbohydr Polym . 2023 Jul; 318:121128. PMID: 37479440
Fucoidans are complex fucose-containing sulfated polysaccharides with pronounced anticancer effects. Their structure-anticancer activity relationships are difficult to determine due to fucoidans' complex, often irregularities-including structures. Fucoidan-active enzymes can be used...
4.
Thinh P, Rasin A, Silchenko A, Trung V, Kusaykin M, Thuy Hang C, et al.
Int J Biol Macromol . 2023 May; 242(Pt 3):124714. PMID: 37148937
Two pectins from the seagrass Enhalus acoroides (L.f.) Royle were isolated for the first time. Their structures and biological activities were investigated. NMR spectroscopy showed one of them to consist...
5.
Zueva A, Usoltseva R, Malyarenko O, Surits V, Silchenko A, Anastyuk S, et al.
Int J Biol Macromol . 2022 Nov; 225:648-657. PMID: 36395953
Six fucoidan fractions were isolated from the brown alga Alaria angusta. Structures of enzymatic hydrolysis products of the fraction 1AaF2 (Fuc:Gal ~ 1:1; 33 % of sulfates) by fucanase from...
6.
Silchenko A, Rubtsov N, Zueva A, Kusaykin M, Rasin A, Ermakova S
Arch Biochem Biophys . 2022 Aug; 728:109373. PMID: 35940339
In present work we provide the bioinformatic and biochemical characterization of six α-L-fucosidases that belong to the 29 and 95 families of glycoside hydrolases (GH) from the fucoidan-degrading locus of...
7.
Usoltseva R, Shevchenko N, Silchenko A, Anastyuk S, Zvyagintsev N, Ermakova S
Int J Biol Macromol . 2022 Feb; 206:614-620. PMID: 35219778
The fucoidan SdeF was isolated from brown alga Saccharina dentigera. The structure of the obtained polysaccharide was studied by chemical methods, NMR spectroscopy of the fully and partially desulfated derivatives,...
8.
Krylova N, Silchenko A, Pott A, Ermakova S, Iunikhina O, Rasin A, et al.
Mar Drugs . 2021 Oct; 19(10). PMID: 34677476
The Hantaan orthohantavirus (genovariant Amur-AMRV) is a rodent-borne zoonotic virus; it is the causative agent of haemorrhagic fever with renal syndrome in humans. The currently limited therapeutic options require the...
9.
Rasin A, Shevchenko N, Silchenko A, Kusaykin M, Likhatskaya G, Zvyagintseva T, et al.
Int J Biol Macromol . 2021 Jul; 185:679-687. PMID: 34216666
Chitosan/fucoidan nanoparticles were created using two fucoidans from the Fucus evanescens algae. One of them was a regular fucoidan obtained for the first time from the alga harvested at the...
10.
Malyarenko O, Malyarenko T, Usoltseva R, Silchenko A, Kicha A, Ivanchina N, et al.
Int J Biol Macromol . 2021 Jun; 185:31-39. PMID: 34144063
This study was aimed to determine the efficacy of combination of fucoidan from the brown algae Fucus evanescens (FeF) or its derivatives with thornasteroside A (ThA) or asteropsiside A (AsA)...