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Arne Schaefer

Explore the profile of Arne Schaefer including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 341
Followers 0
Related Specialties
General Medicine
Biochemistry
Cell Biology
Top 10 Co-Authors
Stefan Schreiber
Heribert Schunkert
Klaus Stark
Nursen Duzgun
Patrick Linsel-Nitschke
Patrick Coit
Sibel P Yentur
Anke Hinney
Meriam Messedi
Florian Kronenberg
Published In
PLoS One
Eur J Hum Genet
Cells
Atherosclerosis
Arthritis Rheumatol
Affiliations
Soon will be listed here.
Recent Articles
1.
Host Genetics Background Affects Intestinal Cancer Development Associated with High-Fat Diet-Induced Obesity and Type 2 Diabetes
Ghnaim A, Midlej K, Zohud O, Karram S, Schaefer A, Houri-Haddad Y, et al.
Cells . 2024 Nov; 13(21. PMID: 39513912
Background: Obesity and type 2 diabetes (T2D) promote inflammation, increasing the risk of colorectal cancer (CRC). High-fat diet (HFD)-induced obesity is key to these diseases through biological mechanisms. This study...
2.
Sex-specific analysis in Behçet's disease reveals higher genetic risk in male patients
Jo Y, Ortiz-Fernandez L, Coit P, Yilmaz V, Yentur S, Alibaz-Oner F, et al.
J Autoimmun . 2022 Aug; 132:102882. PMID: 35987173
Objectives: Behçet's disease tends to be more severe in men than women. This study was undertaken to investigate sex-specific genetic effects in Behçet's disease. Methods: A total of 1762 male...
3.
Genetic Association of a Gain-of-Function IFNGR1 Polymorphism and the Intergenic Region LNCAROD/DKK1 With Behçet's Disease
Ortiz Fernandez L, Coit P, Yilmaz V, Yentur S, Alibaz-Oner F, Aksu K, et al.
Arthritis Rheumatol . 2021 Jan; 73(7):1244-1252. PMID: 33393726
Objective: Behçet's disease is a complex systemic inflammatory vasculitis of incompletely understood etiology. This study was undertaken to investigate genetic associations with Behçet's disease in a diverse multiethnic population. Methods:...
4.
Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach
Versmissen J, Oosterveer D, Yazdanpanah M, Dehghan A, Holm H, Erdman J, et al.
Eur J Hum Genet . 2014 Jun; 23(3):381-7. PMID: 24916650
Mutations in the low-density lipoprotein receptor (LDLR) gene cause familial hypercholesterolemia (FH), a disorder characterized by coronary heart disease (CHD) at young age. We aimed to apply an extreme sampling...
5.
Toward the blood-borne miRNome of human diseases
Keller A, Leidinger P, Bauer A, ElSharawy A, Haas J, Backes C, et al.
Nat Methods . 2011 Sep; 8(10):841-3. PMID: 21892151
In a multicenter study, we determined the expression profiles of 863 microRNAs by array analysis of 454 blood samples from human individuals with different cancers or noncancer diseases, and validated...
6.
Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease
Linsel-Nitschke P, Heeren J, Aherrahrou Z, Bruse P, Gieger C, Illig T, et al.
Atherosclerosis . 2009 Aug; 208(1):183-9. PMID: 19660754
Background: A single nucleotide polymorphism (SNP) rs599839 located at chromosome 1p13.3 has previously been associated with risk of coronary artery disease (CAD) and with serum levels of low-density lipoprotein cholesterol...
7.
Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study
Linsel-Nitschke P, Gotz A, Erdmann J, Braenne I, Braund P, Hengstenberg C, et al.
PLoS One . 2008 Aug; 3(8):e2986. PMID: 18714375
Background: Rare mutations of the low-density lipoprotein receptor gene (LDLR) cause familial hypercholesterolemia, which increases the risk for coronary artery disease (CAD). Less is known about the implications of common...