Arnaud Chignon
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Explore the profile of Arnaud Chignon including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
190
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Recent Articles
1.
Chignon A, Lettre G
Atherosclerosis
. 2025 Feb;
401:118621.
PMID: 39909615
Coronary artery disease (CAD) is due to atherosclerosis, a pathophysiological process that involves several cell-types and results in the accumulation of lipid-rich plaque that disrupt the normal blood flow through...
2.
Chignon A, Mathieu S, Rufiange A, Argaud D, Voisine P, Bosse Y, et al.
Hum Genomics
. 2022 Mar;
16(1):8.
PMID: 35246263
Coronary artery disease (CAD) is a multifactorial disorder, which is partly heritable. Herein, we implemented a mapping of CAD-associated candidate genes by using genome-wide enhancer-promoter conformation (H3K27ac-HiChIP) and expression quantitative...
3.
Chignon A, Argaud D, Boulanger M, Mkannez G, Bon-Baret V, Li Z, et al.
PLoS Genet
. 2022 Jan;
18(1):e1010010.
PMID: 35041643
Calcific aortic valve disease (CAVD) is characterized by a fibrocalcific process. The regulatory mechanisms that drive the fibrotic response in the aortic valve (AV) are poorly understood. Long noncoding RNAs...
4.
Chignon A, Mathieu P
Can J Cardiol
. 2021 Jun;
37(9):1310-1311.
PMID: 34147622
No abstract available.
5.
Valette K, Li Z, Bon-Baret V, Chignon A, Berube J, Eslami A, et al.
Commun Biol
. 2021 Jun;
4(1):700.
PMID: 34103634
To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls)....
6.
Chignon A, Rosa M, Boulanger M, Argaud D, Devillers R, Bon-Baret V, et al.
iScience
. 2021 Mar;
24(3):102241.
PMID: 33748722
Genome-wide association studies for calcific aortic valve stenosis (CAVS) previously reported strong signal for noncoding variants at 1p21.2. Previous study using Mendelian randomization suggested that the locus controls the expression...
7.
Bon-Baret V, Chignon A, Boulanger M, Li Z, Argaud D, Arsenault B, et al.
Circ Genom Precis Med
. 2021 Feb;
14(2):e003196.
PMID: 33625251
Background: Randomized clinical trials indicate that the immune response plays a significant role in coronary artery disease (CAD), a disorder impacting the lifespan potential. However, the identification of targets critical...
8.
Chignon A, Bon-Baret V, Boulanger M, Bosse Y, Mathieu P
Arterioscler Thromb Vasc Biol
. 2020 Nov;
41(1):11-19.
PMID: 33232199
Mineralization of cardiovascular structures including blood vessels and heart valves is a common feature. We postulate that ectopic mineralization is a response-to-injury in which signals delivered to cells trigger a...
9.
Bon-Baret V, Chignon A, Boulanger M, Mathieu P
Arterioscler Thromb Vasc Biol
. 2020 Jul;
40(8):1804-1807.
PMID: 32697681
No abstract available.
10.
Chignon A, Bon-Baret V, Boulanger M, Li Z, Argaud D, Bosse Y, et al.
Commun Biol
. 2020 May;
3(1):206.
PMID: 32358504
The human lifespan is a heritable trait, which is intricately linked to the development of disorders. Here, we show that genetic associations for the parental lifespan are enriched in open...