Armida Faella
Overview
Explore the profile of Armida Faella including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
11
Citations
481
Followers
0
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Recent Articles
1.
Hermosilla-Albala N, Silva F, Cuadros-Espinoza S, Fontsere C, Valenzuela-Seba A, Pawar H, et al.
Commun Biol
. 2024 Oct;
7(1):1283.
PMID: 39379612
Despite showing the greatest primate diversity on the planet, genomic studies on Amazonian primates show very little representation in the literature. With 48 geolocalized high coverage whole genomes from wild...
2.
Esteller-Cucala P, Palmada-Flores M, Kuderna L, Fontsere C, Serres-Armero A, Dabad M, et al.
Commun Biol
. 2023 Jun;
6(1):623.
PMID: 37296226
Recent advances in long-read sequencing technologies have allowed the generation and curation of more complete genome assemblies, enabling the analysis of traditionally neglected chromosomes, such as the human Y chromosome...
3.
di Domenico A, Carola G, Calatayud C, Pons-Espinal M, Munoz J, Richaud-Patin Y, et al.
Stem Cell Reports
. 2019 Jan;
12(2):213-229.
PMID: 30639209
Parkinson's disease (PD) is associated with the degeneration of ventral midbrain dopaminergic neurons (vmDAns) and the accumulation of toxic α-synuclein. A non-cell-autonomous contribution, in particular of astrocytes, during PD pathogenesis...
4.
Marcos-Contreras O, Smith S, Bellinger D, Raymer R, Merricks E, Faella A, et al.
Blood
. 2015 Dec;
127(5):565-71.
PMID: 26702064
Factor VII (FVII) deficiency is a rare autosomal recessive bleeding disorder treated by infusion of fresh-frozen plasma, plasma-derived FVII concentrates and low-dose recombinant activated FVII. Clinical data suggest that a...
5.
Pavani G, Ivanciu L, Faella A, Marcos-Contreras O, Margaritis P
Blood
. 2014 Jun;
124(7):1157-65.
PMID: 24957146
Recombinant activated human factor VII (rhFVIIa) is an established hemostatic agent in hemophilia, but its mechanism of action remains unclear. Although tissue factor (TF) is its natural receptor, rhFVIIa also...
6.
Mingozzi F, Anguela X, Pavani G, Chen Y, Davidson R, Hui D, et al.
Sci Transl Med
. 2013 Jul;
5(194):194ra92.
PMID: 23863832
Adeno-associated virus (AAV) vectors delivered through the systemic circulation successfully transduce various target tissues in animal models. However, similar attempts in humans have been hampered by the high prevalence of...
7.
Margaritis P, Roy E, Faella A, Downey H, Ivanciu L, Pavani G, et al.
Blood
. 2011 Feb;
117(15):3974-82.
PMID: 21325603
Catalytic domain variants of activated factor VII (FVIIa) with enhanced hemostatic properties are highly attractive for the treatment of bleeding disorders via gene-based therapy. To explore this in a hemophilic...
8.
Cotugno G, Annunziata P, Tessitore A, OMalley T, Capalbo A, Faella A, et al.
Mol Ther
. 2010 Dec;
19(3):461-9.
PMID: 21119624
Mucopolysaccharidosis VI (MPS VI) is caused by deficient arylsulfatase B (ARSB) activity resulting in lysosomal storage of glycosaminoglycans (GAGs). MPS VI is characterized by dysostosis multiplex, organomegaly, corneal clouding, and...
9.
Cotugno G, Aurilio M, Annunziata P, Capalbo A, Faella A, Rinaldi V, et al.
Hum Gene Ther
. 2010 Sep;
22(2):189-96.
PMID: 20825281
Noninvasive in vivo imaging of gene expression is desirable to monitor gene transfer in both animal models and humans. Reporter transgenes with low endogenous expression levels are instrumental to this...
10.
Cotugno G, Tessitore A, Capalbo A, Annunziata P, Strisciuglio C, Faella A, et al.
Hum Gene Ther
. 2009 Dec;
21(5):555-69.
PMID: 20021231
Mucopolysaccharidoses (MPSs) are lysosomal storage disorders characterized by progressive accumulation of glycosaminoglycans (GAGs) in various tissues. Enzyme replacement therapy (ERT) for several MPSs is available to date. However, the efficacy...