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Arman Saparov

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Articles 35
Citations 1068
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Recent Articles
1.
Sekenova A, Li Y, Issabekova A, Saparov A, Ogay V
Cells . 2023 Sep; 12(18). PMID: 37759485
Atherosclerosis (AS) is an inflammatory disease involving multiple factors in its initiation and development. In recent years, the potential application of mesenchymal stem cells (MSCs) for treating AS has been...
2.
Kim Y, Zharkinbekov Z, Raziyeva K, Tabyldiyeva L, Berikova K, Zhumagul D, et al.
Pharmaceutics . 2023 Mar; 15(3). PMID: 36986668
Chitosan is a chitin-derived biopolymer that has shown great potential for tissue regeneration and controlled drug delivery. It has numerous qualities that make it attractive for biomedical applications such as...
3.
Sarsenova M, Kim Y, Raziyeva K, Kazybay B, Ogay V, Saparov A
Front Immunol . 2022 Oct; 13:1010399. PMID: 36211399
Considering the unique therapeutic potential of mesenchymal stem cells (MSCs), including their immunosuppressive and immunomodulatory properties as well as their ability to improve tissue regeneration, these cells have attracted the...
4.
Raziyeva K, Kim Y, Zharkinbekov Z, Temirkhanova K, Saparov A
Biomedicines . 2022 Sep; 10(9). PMID: 36140279
Cardiac fibrosis is a common pathological consequence of most myocardial diseases. It is associated with the excessive accumulation of extracellular matrix proteins as well as fibroblast differentiation into myofibroblasts in...
5.
Jimi S, Yoshimura M, Mashima K, Ueda Y, Miyazaki M, Saparov A
Microorganisms . 2022 Feb; 10(2). PMID: 35208802
We investigated the drug-resistant mechanisms of intracellular survival of methicillin-resistant (MRSA). Our established MRSA clinical strain, OJ-1, with high biofilm-forming ability, and a macrophage cell line, J774A, were used. After...
6.
Berillo D, Zharkinbekov Z, Kim Y, Raziyeva K, Temirkhanova K, Saparov A
Pharmaceutics . 2021 Dec; 13(12). PMID: 34959332
Despite their conventional and widespread use, oral and intravenous routes of drug administration face several limitations. In particular, orally administered drugs undergo enzymatic degradation in the gastrointestinal tract and first-pass...
7.
Berillo D, Yeskendir A, Zharkinbekov Z, Raziyeva K, Saparov A
Medicina (Kaunas) . 2021 Nov; 57(11). PMID: 34833427
Peptide-based drug delivery systems have many advantages when compared to synthetic systems in that they have better biocompatibility, biochemical and biophysical properties, lack of toxicity, controlled molecular weight via solid...
8.
Sarsenova M, Issabekova A, Abisheva S, Rutskaya-Moroshan K, Ogay V, Saparov A
Int J Mol Sci . 2021 Nov; 22(21). PMID: 34769021
Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to their progenitor characteristics, MSCs...
9.
Jimi S, Saparov A, Koizumi S, Miyazaki M, Takagi S
J Vet Med Sci . 2021 Nov; 83(12):1933-1942. PMID: 34719609
Hypertrophic scars found on the human body rarely develop in experimental animals, possibly due to their looser skin structure. This makes it difficult to understand the genesis of scar lesions....
10.
Jimi S, Koizumi S, Sato K, Miyazaki M, Saparov A
Sci Rep . 2021 Sep; 11(1):18750. PMID: 34548594
Collagens act as cellular scaffolds in extracellular matrixes, and their breakdown products may also have important biological functions. We hypothesize that collagen dipeptide Pro-Hyp induces favorable healing activities and examined...