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Arjen F Nikkels

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Articles 74
Citations 373
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Recent Articles
1.
Bailleux S, Cao S, Dezfoulian B, Collins P, Somja J, Gatineau S, et al.
Case Rep Dermatol . 2025 Feb; 16(1):248-253. PMID: 39981006
Introduction: Aleukemic leukemia cutis (ALC) is a rare condition and concerns less than 10% of leukemia cutis (LC) cases. LC is defined as a cutaneous infiltration of neoplastic myeloid or...
2.
Damsin T, Absil G, Libon F, Tassoudji N, Nikkels A
Psoriasis (Auckl) . 2025 Jan; 15():1-8. PMID: 39781106
Background: Biological therapies, including TNF-alpha, IL12/23, IL17 and IL23 antagonists, adequately control a very high number of patients with moderate-to-severe psoriasis with an excellent long-term safety profile. However, on occasion,...
3.
Libon F, Caron J, Nikkels A
Dermatol Ther (Heidelb) . 2024 Jun; 14(7):1729-1738. PMID: 38874894
Atopic dermatitis (AD) is a chronic inflammatory skin condition. The pathogenesis involves genetic, environmental, and immunological factors as well as a barrier dysfunction of the epidermis. Biomarkers may play a...
4.
Nikkels A, Schoevaerdts D, Kauffmann F, Strubbe F, Bensemmane S
Acta Clin Belg . 2024 May; 79(3):205-216. PMID: 38781037
Herpes zoster (HZ) is caused by reactivation of the varicella-zoster virus. The life-time risk of developing HZ is ~ 30%. Management of HZ can be challenging due to limited efficacy...
5.
Lebas E, Collins P, Somja J, Nikkels A
Dermatology . 2023 Aug; 239(6):860-867. PMID: 37611553
Background: The advancing evolution toward a Th2 immune environment confers a progressive immunosuppression in patients with longstanding cutaneous T-cell lymphoma (CTCL). The conjunction of the disease-related immunosuppression as well as...
6.
Sticherling M, Nikkels A, Hamza A, Kwong P, Szepietowski J, El Sayed M, et al.
Am J Clin Dermatol . 2023 Jun; 24(5):821-835. PMID: 37341961
Background: Plaque psoriasis affects ~ 1% of the pediatric population, negatively impacting quality of life. The efficacy and safety of secukinumab in pediatric patients with moderate to severe or severe...
7.
Progneaux A, Evrard C, De Glas V, Fontaine A, Dotreppe C, De Vuyst E, et al.
Exp Dermatol . 2023 Jan; 32(5):660-670. PMID: 36645024
Atopic dermatitis (AD) is a Th2-type inflammatory disease characterized by an alteration of epidermal barrier following the release of IL-4 and IL-13. These cytokines activate type II IL-4Rα/IL-13Rα1 receptors in...
8.
Bailleux S, Collins P, Nikkels A
Dermatol Ther (Heidelb) . 2022 Apr; 12(5):1103-1119. PMID: 35430724
Introduction: Non-dermatology medical specialties may refer patients for skin biopsies, searching for a particular diagnosis. However, the diagnostic impact of the skin biopsy is not clearly established. This article aims...
9.
Damsin T, Lebas E, Marchal N, Rorive A, Nikkels A
Expert Rev Anticancer Ther . 2022 Feb; 22(3):243-248. PMID: 35175882
Introduction: Locally advanced basal cell carcinoma (laBCC) represents approximatively 1% of all BCCs. Metastatic BCC (mBCC) is even more rare. Most cases are observed in immunocompromised patients, particularly solid organ...
10.
Lebas E, Collins P, Somja J, Nikkels A
Dermatol Ther (Heidelb) . 2021 Oct; 11(6):1931-1951. PMID: 34709600
Introduction: Mycosis fungoides (MF) is the most frequent subtype of primary cutaneous T cell lymphomas (pCTCL). The diagnosis may be particularly difficult in the early stages as well as in...