Areles Molleman
Overview
Explore the profile of Areles Molleman including associated specialties, affiliations and a list of published articles.
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12
Citations
345
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Recent Articles
1.
Thiemann G, Watt C, Ledent C, Molleman A, Hasenohrl R
Behav Brain Res
. 2009 Jan;
200(1):60-7.
PMID: 19162082
The CB(1) cannabinoid receptor has been implicated in the control of fear and anxiety. We investigated the effects of genetic and pharmacological blockade of the CB(1) cannabinoid receptor on the...
2.
Thiemann G, Di Marzo V, Molleman A, Hasenohrl R
Pharmacol Biochem Behav
. 2008 Feb;
89(3):384-91.
PMID: 18294680
Endogenous cannabinoids modulate the activity of dopamine reward pathways and may play a role in the development of behavioural sensitization to psychostimulants. Here, we investigated the effects of the CB(1)...
3.
Thiemann G, van der Stelt M, Petrosino S, Molleman A, Di Marzo V, Hasenohrl R
Behav Brain Res
. 2007 Nov;
187(2):289-96.
PMID: 17988751
Cannabinoid receptors and their endogenous ligands (endocannabinoids) have been implicated in cocaine and amphetamine reward. Their role in psychostimulant-induced behavioural sensitization still has to be determined. The purpose of the...
4.
Thiemann G, Fletcher B, Ledent C, Molleman A, Hasenohrl R
Neurobiol Learn Mem
. 2007 Sep;
88(4):416-23.
PMID: 17884611
The endocannabinoid CB(1) receptor has been implicated in the inhibitory control of learning and memory. In the present experiment, we compared the behavioral response of CB(1) receptor knockout mice (CB(1)R(-/-))...
5.
Mormina M, Thakur S, Molleman A, Whelan C, Baydoun A
Eur J Pharmacol
. 2006 May;
540(1-3):183-90.
PMID: 16714014
The molecular events mediating the immunomodulatory properties of cannabinoids have remained largely unresolved. We have therefore investigated the molecular mechanism(s) through which R-(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl] pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-napthanlenyl) methanone (WIN55212-2) modulate production of interleukin-8...
6.
Demuth D, Molleman A
Life Sci
. 2005 Aug;
78(6):549-63.
PMID: 16109430
After their discovery, the two known cannabinoid receptors, CB(1) and CB(2), have been the focus of research into the cellular signalling mechanisms of cannabinoids. The initial assessment, mainly derived from...
7.
Demuth D, Gkoumassi E, Droge M, Dekkers B, Esselink H, van Ree R, et al.
J Cell Physiol
. 2005 May;
205(1):58-67.
PMID: 15887237
Cannabinoid CB1-receptor stimulation in DDT1 MF-2 smooth muscle cells induces a rise in [Ca2+]i, which is dependent on extracellular Ca2+ and modulated by thapsigargin-sensitive stores, suggesting capacitative Ca2+ entry (CCE),...
8.
Forrest A, Molleman A, Parsons M
Eur J Pharmacol
. 2005 Feb;
509(1):77-83.
PMID: 15713432
Studies were performed to see if alterations in Ca2+ homeostasis underlie the gastrointestinal motility complications seen in many diabetic patients. Experiments were performed on colonic and ileal tissues taken from...
9.
Ihenetu K, Molleman A, Parsons M, Whelan C
Eur J Pharmacol
. 2003 Mar;
464(2-3):207-15.
PMID: 12620515
The effects of a range of cannabinoid receptor agonists and antagonists on phytohaemagglutinin-induced secretion of interleukin-2 from human peripheral blood mononuclear cells were investigated. The nonselective cannabinoid receptor agonist WIN55212-2...
10.
Ihenetu K, Molleman A, Parsons M, Whelan C
Eur J Pharmacol
. 2002 Dec;
458(1-2):207-15.
PMID: 12498928
We have investigated the effects of cannabinoid agonists and antagonists on tumour necrosis factor-alpha (TNF-alpha)-induced secretion of interleukin-8 from the colonic epithelial cell line, HT-29. The cannabinoid receptor agonists [(-)-3-[2-hydroxy-4-(1,1-dimethyl-heptyl)-phenyl]4-[3-hydroxypropyl]cyclo-hexan-1-ol]...