Aravindakshan Parthasarathy
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Explore the profile of Aravindakshan Parthasarathy including associated specialties, affiliations and a list of published articles.
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26
Citations
431
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Recent Articles
1.
McHaney J, Hancock K, Polley D, Parthasarathy A
Sci Rep
. 2024 Dec;
14(1):30882.
PMID: 39730737
Multi-talker speech intelligibility requires successful separation of the target speech from background speech. Successful speech segregation relies on bottom-up neural coding fidelity of sensory information and top-down effortful listening. Here,...
2.
Parida S, Yurasits K, Cancel V, Zink M, Mitchell C, Ziliak M, et al.
Commun Biol
. 2024 Nov;
7(1):1517.
PMID: 39548272
Current tests of hearing fail to diagnose pathologies in ~10% of patients seeking help for hearing difficulties. Neural ensemble responses to perceptually relevant cues in the amplitude envelope, termed envelope...
3.
Guo Z, McHaney J, Parthasarathy A, Chandrasekaran B
bioRxiv
. 2024 Sep;
PMID: 39253477
Speech perception declines independent of hearing thresholds in middle-age, and the neurobiological reasons are unclear. In line with the age-related neural dedifferentiation hypothesis, we predicted that middle-aged adults show less...
4.
Zink M, Zhen L, McHaney J, Klara J, Yurasits K, Cancel V, et al.
bioRxiv
. 2024 Aug;
PMID: 39149285
Middle-age is a critical period of rapid changes in brain function that presents an opportunity for early diagnostics and intervention for neurodegenerative conditions later in life. Hearing loss is one...
5.
Bartlett E, Han E, Parthasarathy A
Hear Res
. 2024 May;
447:109028.
PMID: 38733711
Amplitude modulation is an important acoustic cue for sound discrimination, and humans and animals are able to detect small modulation depths behaviorally. In the inferior colliculus (IC), both firing rate...
6.
Parida S, Yurasits K, Cancel V, Zink M, Mitchell C, Ziliak M, et al.
bioRxiv
. 2024 Feb;
PMID: 38352339
Auditory neural coding of speech-relevant temporal cues can be noninvasively probed using envelope following responses (EFRs), neural ensemble responses phase-locked to the stimulus amplitude envelope. EFRs emphasize different neural generators,...
7.
McHaney J, Hancock K, Polley D, Parthasarathy A
bioRxiv
. 2023 Aug;
PMID: 37645975
Optimal speech perception in noise requires successful separation of the target speech stream from multiple competing background speech streams. The ability to segregate these competing speech streams depends on the...
8.
Cancel V, McHaney J, Milne V, Palmer C, Parthasarathy A
Sci Rep
. 2023 Aug;
13(1):13636.
PMID: 37604867
Hearing thresholds form the gold standard assessment in Audiology clinics. However, ~ 10% of adult patients seeking audiological care for self-perceived hearing deficits have thresholds that are normal. Currently, a...
9.
McGill M, Hight A, Watanabe Y, Parthasarathy A, Cai D, Clayton K, et al.
Elife
. 2022 Sep;
11.
PMID: 36111669
Neurons in sensory cortex exhibit a remarkable capacity to maintain stable firing rates despite large fluctuations in afferent activity levels. However, sudden peripheral deafferentation in adulthood can trigger an excessive,...
10.
Grant K, Parthasarathy A, Vasilkov V, Caswell-Midwinter B, Freitas M, de Gruttola V, et al.
Sci Rep
. 2022 Jun;
12(1):8929.
PMID: 35739134
The current gold standard of clinical hearing assessment includes a pure-tone audiogram combined with a word recognition task. This retrospective study tests the hypothesis that deficits in word recognition that...