Arash Grakoui
Overview
Explore the profile of Arash Grakoui including associated specialties, affiliations and a list of published articles.
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Articles
89
Citations
4123
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Recent Articles
1.
Eisa M, Flores N, Khedr O, Gomez-Escobar E, Bedard N, Abdeltawab N, et al.
Viruses
. 2024 Oct;
16(10).
PMID: 39459954
Identification and isolation of antigen-specific T cells for downstream transcriptomic analysis is key for various immunological studies. Traditional methods using major histocompatibility complex (MHC) multimers are limited by the number...
2.
Jin F, Gridley J, Kumari A, Saeidi A, Holland B, Elrod E, et al.
J Hepatol
. 2024 Oct;
PMID: 39423870
Background & Aims: The most recent T cell-based vaccine against HCV tested in humans failed to swing the pendulum from chronicity to resolution, despite eliciting cellular responses in most individuals....
3.
Moore K, Foster S, Kar M, Floyd K, Elrod E, Williams M, et al.
bioRxiv
. 2024 Aug;
PMID: 39211190
Waning immunity and the emergence of immune evasive SARS-CoV-2 variants jeopardize vaccine efficacy leading to breakthrough infections. We have previously shown that innate immune cells play a critical role in...
4.
Kar M, Johnson K, Vanderheiden A, Elrod E, Floyd K, Geerling E, et al.
Sci Adv
. 2024 Aug;
10(34):eadp2636.
PMID: 39178263
SARS-CoV-2 infection induces the generation of virus-specific CD4 and CD8 effector and memory T cells. However, the contribution of T cells in controlling SARS-CoV-2 during infection is not well understood....
5.
Eisa M, Gomez-Escobar E, Bedard N, Abdeltawab N, Flores N, Mazouz S, et al.
Front Immunol
. 2024 Jul;
15:1403769.
PMID: 38947319
Introduction: Follicular helper T cells are essential for helping in the maturation of B cells and the production of neutralizing antibodies (NAbs) during primary viral infections. However, their role during...
6.
Hellen D, Fay M, Lee D, Klindt-Morgan C, Bennett A, Pachura K, et al.
Am J Physiol Gastrointest Liver Physiol
. 2024 Apr;
327(1):G1-G15.
PMID: 38651949
The progress of research focused on cholangiocytes and the biliary tree during development and following injury is hindered by limited available quantitative methodologies. Current techniques include two-dimensional standard histological cell-counting...
7.
Kar M, Johnson K, Vanderheiden A, Elrod E, Floyd K, Geerling E, et al.
bioRxiv
. 2024 Feb;
PMID: 38410446
SARS-CoV-2 is the causative agent of COVID-19 and continues to pose a significant public health threat throughout the world. Following SARS-CoV-2 infection, virus-specific CD4+ and CD8+ T cells are rapidly...
8.
Gridley J, Holland B, Salinas E, Trivedi S, Dravid P, Elrod E, et al.
Hepatology
. 2024 Jan;
80(4):937-950.
PMID: 38214558
Background And Aims: Evidence assessing the role of B cells and their antibodies, or lack thereof, in the spontaneous resolution of acute HCV infection is conflicting. Utilization of a strictly...
9.
Dravid P, Murthy S, Attia Z, Cassady C, Chandra R, Trivedi S, et al.
PLoS Pathog
. 2023 Oct;
19(10):e1011697.
PMID: 37812637
Immune correlates of hepatitis C virus (HCV) clearance and control remain poorly defined due to the lack of an informative animal model. We recently described acute and chronic rodent HCV-like...
10.
Thapa M, Kumari A, Chin C, Choby J, Jin F, Bogati B, et al.
bioRxiv
. 2023 Sep;
PMID: 37693595
The gut-brain axis, a bidirectional signaling network between the intestine and the central nervous system, is crucial to the regulation of host physiology and inflammation. Recent advances suggest a strong...