Arash Farhadi
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Explore the profile of Arash Farhadi including associated specialties, affiliations and a list of published articles.
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20
Citations
702
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Recent Articles
1.
Hurt R, Buss M, Duan M, Wong K, You M, Sawyer D, et al.
Nat Biotechnol
. 2023 Jan;
41(7):919-931.
PMID: 36593411
Ultrasound allows imaging at a much greater depth than optical methods, but existing genetically encoded acoustic reporters for in vivo cellular imaging have been limited by poor sensitivity, specificity and...
2.
Sawyer D, Bar-Zion A, Farhadi A, Shivaei S, Ling B, Lee-Gosselin A, et al.
Nat Methods
. 2021 Aug;
18(8):945-952.
PMID: 34354290
Acoustic reporter genes (ARGs) that encode air-filled gas vesicles enable ultrasound-based imaging of gene expression in genetically modified bacteria and mammalian cells, facilitating the study of cellular function in deep...
3.
Farhadi A, Sigmund F, Westmeyer G, Shapiro M
Nat Mater
. 2021 Feb;
20(5):585-592.
PMID: 33526879
Many questions in basic biology and medicine require the ability to visualize the function of specific cells and molecules inside living organisms. In this context, technologies such as ultrasound, optoacoustics...
4.
Farhadi A, Bedrossian M, Lee J, Ho G, Shapiro M, Nadeau J
Nano Lett
. 2020 Oct;
20(11):8127-8134.
PMID: 33118828
Quantitative phase imaging and digital holographic microscopy have shown great promise for visualizing the motion, structure, and physiology of microorganisms and mammalian cells in three dimensions. However, these imaging techniques...
5.
Farhadi A, Ho G, Sawyer D, Bourdeau R, Shapiro M
Science
. 2019 Oct;
365(6460):1469-1475.
PMID: 31604277
The study of cellular processes occurring inside intact organisms requires methods to visualize cellular functions such as gene expression in deep tissues. Ultrasound is a widely used biomedical technology enabling...
6.
Farhadi A, Ho G, Kunth M, Ling B, Lakshmanan A, Lu G, et al.
AIChE J
. 2018 Dec;
64(8):2927-2933.
PMID: 30555168
Ultrasound and hyperpolarized magnetic resonance imaging enable the visualization of biological processes in deep tissues. However, few molecular contrast agents are available to connect these modalities to specific aspects of...
7.
Maresca D, Lakshmanan A, Abedi M, Bar-Zion A, Farhadi A, Lu G, et al.
Annu Rev Chem Biomol Eng
. 2018 Mar;
9:229-252.
PMID: 29579400
Visualizing and modulating molecular and cellular processes occurring deep within living organisms is fundamental to our study of basic biology and disease. Currently, the most sophisticated tools available to dynamically...
8.
Lu G, Farhadi A, Mukherjee A, Shapiro M
Curr Opin Chem Biol
. 2018 Mar;
45:57-63.
PMID: 29549770
A long-standing goal of molecular imaging is to visualize cellular function within the context of living animals, necessitating the development of reporter genes compatible with deeply penetrant imaging modalities such...
9.
Lu G, Farhadi A, Szablowski J, Lee-Gosselin A, Barnes S, Lakshmanan A, et al.
Nat Mater
. 2018 Feb;
17(5):456-463.
PMID: 29483636
Non-invasive biological imaging requires materials capable of interacting with deeply penetrant forms of energy such as magnetic fields and sound waves. Here, we show that gas vesicles (GVs), a unique...
10.
Bourdeau R, Lee-Gosselin A, Lakshmanan A, Farhadi A, Kumar S, Nety S, et al.
Nature
. 2018 Jan;
553(7686):86-90.
PMID: 29300010
The mammalian microbiome has many important roles in health and disease, and genetic engineering is enabling the development of microbial therapeutics and diagnostics. A key determinant of the activity of...