Ara Metjian
Overview
Explore the profile of Ara Metjian including associated specialties, affiliations and a list of published articles.
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23
Citations
483
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0
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Recent Articles
11.
Yuan X, Yu J, Gerber G, Chaturvedi S, Cole M, Chen H, et al.
Clin Immunol
. 2020 Nov;
221:108616.
PMID: 33148511
In complement-driven thrombotic microangiopathies, failure to regulate complement activation leads to end-organ damage. The modified Ham (mHam) test measures complement-mediated killing of a nucleated cell in vitro but lacks a...
12.
Hanlon A, Metjian A
Ther Adv Hematol
. 2020 Feb;
11:2040620720902904.
PMID: 32095224
Thrombotic thrombocytopenic purpura (TTP) is usually a fatal disease caused by a deficiency of the metalloproteinase, ADAMTS13, often due to autoimmunity. This leads to the development of pathogenic multimers of...
13.
Knoebl P, Cataland S, Peyvandi F, Coppo P, Scully M, Kremer Hovinga J, et al.
J Thromb Haemost
. 2019 Nov;
18(2):479-484.
PMID: 31691462
Background: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening autoimmune thrombotic microangiopathy. Caplacizumab, an anti-von Willebrand Factor Nanobody , is effective for treating aTTP episodes and is well tolerated....
14.
Zwicker J, Muia J, Dolatshahi L, Westfield L, Nieters P, Rodrigues A, et al.
Blood
. 2019 Jul;
134(13):1106-1109.
PMID: 31331919
No abstract available.
15.
Scully M, Cataland S, Peyvandi F, Coppo P, Knobl P, Kremer Hovinga J, et al.
N Engl J Med
. 2019 Jan;
380(4):335-346.
PMID: 30625070
Background: In acquired thrombotic thrombocytopenic purpura (TTP), an immune-mediated deficiency of the von Willebrand factor-cleaving protease ADAMTS13 allows unrestrained adhesion of von Willebrand factor multimers to platelets and microthrombosis, which...
16.
Diep R, Metjian A
J Thromb Thrombolysis
. 2018 Feb;
45(3):457-462.
PMID: 29411299
Essential thrombocythemia (ET) is an indolent myeloproliferative neoplasm characterized by megakaryocyte hyperplasia, thrombocytosis, thrombotic and hemorrhagic complications, and potential transformation into myelofibrosis and acute myeloid leukemia. The vast majority of...
17.
Abbes S, Metjian A, Gray A, Martinu T, Snyder L, Chen D, et al.
Ther Apher Dial
. 2017 Sep;
21(5):441-450.
PMID: 28880430
The human leukocyte antigen (HLA) system is an important immunologic barrier that must be considered for successful solid organ transplantation. Formation of donor-specific HLA antibodies in solid organ transplantation is...
18.
Tanhehco Y, Arepally G, Metjian A
Curr Opin Hematol
. 2017 Aug;
24(6):521-528.
PMID: 28759473
Purpose Of Review: Acquired thrombotic thrombocytopenic purpura is an immune-mediated thrombotic microangiopathy caused by antibodies to ADAMTS13 (A Disintegrin And Metalloproteinase with a ThromboSpondin type 1 motif, member 13). Standard...
19.
Metjian A, Tanhehco Y, Aqui N, Bhoj V, Jamensky L, Marques M, et al.
J Clin Apher
. 2015 Nov;
31(5):448-53.
PMID: 26575088
The thrombotic microangiopathy (TMA) Registry Network of North America (TRNA) is a collaborative network organized for the purpose of developing a multi-institutional registry and network to conduct clinical studies in...
20.
Nipp R, Mitchell A, Pishko A, Metjian A
Case Rep Oncol Med
. 2014 Sep;
2014:165670.
PMID: 25247100
Background. Recent literature has associated hepatitis C virus with the development of non-Hodgkin lymphoma. Hepatitis C virus infection appears to promote lymphoproliferation, providing a plausible mechanism for a causative association;...