Aprile L Pilon
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Explore the profile of Aprile L Pilon including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
338
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Recent Articles
11.
Wolfson M, Funanage V, Kirwin S, Pilon A, Shashikant B, Miller T, et al.
Am J Perinatol
. 2008 Oct;
25(10):637-45.
PMID: 18841530
Infant respiratory distress syndrome (IRDS) can lead to impaired alveolarization and dysmorphic vascularization of bronchopulmonary dysplasia. Clara cell secretory protein (CC10) has anti-inflammatory properties but is deficient in the premature...
12.
Angert R, Pilon A, Chester D, Davis J
Pediatr Res
. 2007 Oct;
62(6):684-8.
PMID: 17957145
Complications from meconium aspiration syndrome (MAS) remain significant despite a variety of therapeutic interventions. Clara cell protein (CC10) is a novel anti-inflammatory agent that can also inhibit phospholipase A2 (PLA2)...
13.
Miller T, Shashikant B, Pilon A, Pierce R, Shaffer T, Wolfson M
Pediatr Crit Care Med
. 2006 Dec;
8(1):40-6.
PMID: 17149150
Objective: To test the hypothesis that recombinant Clara cell secretory protein (rhCC10) instillation would foster improved lung function, acute structural preservation, and attenuation of matrix metalloproteinase (MMP) activity in a...
14.
Antico G, Lingen M, Sassano A, Melby J, Welch R, Fiore S, et al.
J Cell Physiol
. 2006 Feb;
207(2):553-61.
PMID: 16453303
Uteroglobin (UG) or Clara Cell 10 kDa protein (CC10) is a small, stable, epithelial secretory anti-inflammatory protein. Uteroglobin has been shown to inhibit neointimal formation in vivo after balloon angioplasty...
15.
Miller T, Shashikant B, Melby J, Pilon A, Shaffer T, Wolfson M
Pediatr Crit Care Med
. 2005 Nov;
6(6):698-706.
PMID: 16276338
Objective: To test the hypothesis that intratracheal instillation of Clara cell secretory protein (CC 10) to the lung may afford greater protection than intravenous administration from ventilator-induced lung inflammation. Design:...
16.
Miller T, Shashikant B, Pilon A, Pierce R, Shaffer T, Wolfson M
Biol Neonate
. 2005 Oct;
89(3):159-70.
PMID: 16210850
Background: Mechanical ventilation results in acute lung trauma that can stimulate processes that alter lung development. Activation of matrix metalloproteinases (MMPs) and their tissue-produced inhibitors (TIMPs) is initiated by the...
17.
Shashikant B, Miller T, Welch R, Pilon A, Shaffer T, Wolfson M
J Appl Physiol (1985)
. 2005 Aug;
99(6):2204-11.
PMID: 16081627
While surfactant (SF) therapy alone improves respiratory distress syndrome (RDS)-associated gas exchange and lung stability, absence of anti-inflammatory proteins limits efficacy with respect to inflammation. Clara cell secretory protein (CC10),...
18.
Levine C, Gewolb I, Allen K, Welch R, Melby J, Pollack S, et al.
Pediatr Res
. 2005 Mar;
58(1):15-21.
PMID: 15774846
Clara cell 10-kD protein (CC10) is a potent anti-inflammatory protein that is normally abundant in the respiratory tract. CC10 is deficient and oxidized in premature infants with poor clinical outcome...