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Appadurai Muthamil Iniyan

Explore the profile of Appadurai Muthamil Iniyan including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 49
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Recent Articles
1.
Deepak Shyl E, Malgija B, Iniyan A, Mahendran R, Vincent S
Heliyon . 2022 Oct; 8(10):e11123. PMID: 36299526
Acute Myeloid Leukemia (AML) is a heterogeneous disease with highest mortality compared to other types of leukemia. There is a need to find the gene abnormalities and mechanisms behind them...
2.
Deepak Shyl E, Malgija B, Iniyan A, Vincent S
Proteins . 2022 Apr; 90(9):1699-1713. PMID: 35429048
Myeloid cell leukemia-1 (MCL1), an anti-apoptotic BCL-2 family protein plays a major role in the control of apoptosis as the regulator of mitochondrial permeability which is deregulated in various solid...
3.
Jabila Mary T, Kannan R, Iniyan A, Ramachandran D, Vincent S
Microb Pathog . 2020 Dec; 150:104712. PMID: 33359358
The emergence of life threatening antibiotic resistant pathogens and its associated mortality and morbidity necessitates many new antibiotics from diverse ecological habitats. Marine sponge associated microbes are promising to provide...
4.
Jabila Mary T, Kannan R, Iniyan A, Carlton Ranjith W, Nandhagopal S, Vishwakarma V, et al.
Microbiol Res . 2020 Dec; 244:126666. PMID: 33338970
β-lactamase inhibitors are potent synergistic drugs to deteriorate the multidrug-resistant bacteria. Here, we report the β-lactamase inhibitory ability of kalafungin isolated from a marine sponge derived Streptomyces sp. SBRK1. The...
5.
Iniyan A, Wink J, Landwehr W, Ramprasad E, Sasikala C, Venkata Ramana C, et al.
J Antibiot (Tokyo) . 2020 Aug; 74(1):59-69. PMID: 32788709
A novel marine actinomycete strain designated ICN19 was isolated from the subtidal sediment of Chinnamuttam coast of Kanyakumari, India and subjected to polyphasic taxonomic analysis. Neighbour-joining tree based on 16S...
6.
Iniyan A, Sudarman E, Wink J, Kannan R, Vincent S
J Antibiot (Tokyo) . 2018 Oct; 72(2):99-105. PMID: 30356080
Bioassay-guided screening of antibacterial compounds from the cultured marine Streptomyces sp. ICN19 provided Ala-geninthiocin (1), along with its known analogs geninthiocin (2) and Val-geninthiocin (3) and the indolocarbazole staurosporine (4)....
7.
Iniyan A, Kannan R, Joseph F, Jabila Mary T, Rajasekar M, Sumy P, et al.
Microb Pathog . 2017 Sep; 112:76-82. PMID: 28943148
Silver chloride nanoparticles were synthesized from the cell-free culture supernatant of Streptomyces strain using green synthesis approach with good yield. The nanoparticles were characterized by UV-Vis, IR, SEM, AFM and...
8.
Joseph F, Iniyan A, Vincent S
Microb Pathog . 2017 Sep; 111:450-457. PMID: 28935203
On the effort to screen antibiotics against Methicillin resistant Staphylococcus aureus (MRSA), an actinomycete strain which can produce bactericidal compound was isolated from a marine sponge of Kanyakumari Coast, India....
9.
Kannan R, Iniyan A, Vincent S
Indian J Pharmacol . 2015 Apr; 47(2):195-8. PMID: 25878381
Objective: Phenotype based small molecule discovery is a category of chemical genetic study. The aim of this study was to observe the phytochemical based genetic effects of Sargassum wightii during...
10.
Kannan R, Iniyan A, Vincent S
Indian J Med Res . 2014 Aug; 139(6):913-20. PMID: 25109726
Background & Objectives: Antibiotic resistance in pathogens has become a serious problem worldwide. Therefore, the search for new antibiotics for drug resistanct pathogens is an important endeavor. The present study...