Aparna Sapra
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Explore the profile of Aparna Sapra including associated specialties, affiliations and a list of published articles.
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3
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18
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Recent Articles
1.
Stull F, Bernard S, Sapra A, Smith J, Zuiderweg E, Palfey B
Biochemistry
. 2016 May;
55(23):3261-9.
PMID: 27214228
Many microorganisms use flavin-dependent thymidylate synthase (FDTS) to synthesize the essential nucleotide 2'-deoxythymidine 5'-monophosphate (dTMP) from 2'-deoxyuridine 5'-monophosphate (dUMP), 5,10-methylenetetrahydrofolate (CH2THF), and NADPH. FDTSs have a structure that is unrelated...
2.
Sapra A, Ramadan D, Thorpe C
Biochemistry
. 2014 Dec;
54(2):612-21.
PMID: 25506675
The renewed use of arsenicals as chemotherapeutics has rekindled interest in the biochemistry of As(III) species. In this work, simple bis- and tris-arsenical derivatives were synthesized with the aim of...
3.
Sapra A, Thorpe C
J Am Chem Soc
. 2013 Feb;
135(7):2415-8.
PMID: 23384038
The finding that arsenic trioxide is an effective treatment for acute promyelocytic leukemia has renewed interest in the pharmacological uses of inorganic and organic arsenicals. Here we synthesized and characterized...