Antonio R Moreira
Overview
Explore the profile of Antonio R Moreira including associated specialties, affiliations and a list of published articles.
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16
Citations
121
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Recent Articles
1.
Stassen M, Leitao C, Manzano T, Valero F, Stevens B, Schmucki M, et al.
PDA J Pharm Sci Technol
. 2024 Dec;
79(1):68-87.
PMID: 39730202
This review paper explores the transformative impact of Artificial Intelligence (AI) on Continued Process Verification (CPV) in the biopharmaceutical industry. Originating from the CPV of the Future project, the study...
2.
Chiba C, Knirsch M, Azzoni A, Moreira A, Stephano M
Biotechniques
. 2021 Jan;
70(2):126-133.
PMID: 33467890
Biopharmaceutical products are of great importance in the treatment or prevention of many diseases and represent a growing share of the global pharmaceutical market. The usual technology for protein synthesis...
3.
Branco F, Machado D, Silva F, Andre S, Catarino A, Madureira R, et al.
Am J Transl Res
. 2019 Oct;
11(9):6110-6116.
PMID: 31632579
Introduction: HER2 overexpression/amplification occurs in 15-20% breast cancers (BC) and is associated with worse prognosis. The addition of anti-HER2 treatment to neoadjuvant chemotherapy significantly improves the pathological complete response (pCR)...
4.
Pinto N, Uplekar S, Moreira A, Rao G, Frey D
Biotechnol Bioeng
. 2016 Jul;
114(1):154-162.
PMID: 27425244
Purification processes for monoclonal Immunoglobulin G (IgG) typically employ protein A chromatography as a capture step to remove most of the impurities. One major concern of the post-protein A chromatography...
5.
Kondragunta B, Joshi B, Han J, Brorson K, Puri R, Moreira A, et al.
Biotechnol Prog
. 2012 Aug;
28(5):1138-51.
PMID: 22848039
Scale-down of bioreactors is currently done based on matching one or more measurable parameters such as k(L) a and P/V, which could result in insufficient process comparability. Currently, there is...
6.
Kondragunta B, Han J, Joshi B, Brorson K, Puri R, Uplekar S, et al.
Biotechnol Prog
. 2012 Jul;
28(5):1126-37.
PMID: 22837152
Currently, there is a gap in the knowledge of the culture responses to controlled bioreactor environment during the course of batch cell culture from early exponential phase to stationary-phase. If...
7.
Vallejos J, Uplekar S, da Silva J, Brorson K, Moreira A, Rao G
Biotechnol Bioeng
. 2012 May;
109(11):2790-7.
PMID: 22549482
In this study, we perform mass transfer characterization (k(L) a) on a novel mechanically driven/stirred Process Scouting Device, PSD, (SuperSpinner D 1000®, SSD) and demonstrate that this novel device can...
8.
Vallejos J, Micheletti M, Brorson K, Moreira A, Rao G
Biotechnol Bioeng
. 2012 Apr;
109(9):2295-305.
PMID: 22473759
During the past decade, novel disposable cell culture vessels (generally referred to as Process Scouting Devices or PSDs) have become increasingly popular for laboratory scale studies and seed culture generation....
9.
Passos-Coelho J, Esteves S, Vieira P, Isidoro M, Ribeiro M, Oliveira J, et al.
Breast J
. 2011 Sep;
17(5):539-41.
PMID: 21899649
No abstract available.
10.
Vallejos J, Brorson K, Moreira A, Rao G
Biotechnol Prog
. 2011 Apr;
27(3):803-10.
PMID: 21523928
The bioprocess development cycle is a complex task that requires a complete understanding of the engineering of the process (e.g., mass transfer, mixing, CO(2) removal, process monitoring, and control) and...