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Antonio Francisco Alves da Silva

Explore the profile of Antonio Francisco Alves da Silva including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 63
Followers 0
Related Specialties
General Medicine
Genetics
Science
Top 10 Co-Authors
Enrique Medina-Acosta
Cintia Barros Santos-Reboucas
Filipe Brum Machado
Douglas Terra Machado
Guy Froyen
Pedro Thyago Mozer Rodrigues
Ronaldo da Silva Francisco Junior
Marcia Goncalves Ribeiro
Marcia Mattos Goncalves Pimentel
Luciana Guedes de Almeida
Published In
PLoS One
Eur J Hum Genet
Front Genet
J Hum Genet
Affiliations
Soon will be listed here.
Recent Articles
1.
Maternal 5CpG Imprints at the and Differentially Methylated Regions Are Decoupled From Parent-of-Origin Expression Effects in Multiple Human Tissues
de Sa Machado Araujo G, da Silva Francisco Junior R, Dos Santos Ferreira C, Mozer Rodrigues P, Machado D, Louvain de Souza T, et al.
Front Genet . 2018 Mar; 9:36. PMID: 29545821
A hallmark of imprinted genes in mammals is the occurrence of parent-of-origin-dependent asymmetry of DNA cytosine methylation (5C) of alleles at CpG islands (CGIs) in their promoter regions. This 5CpG...
2.
Trisomy 21 Alters DNA Methylation in Parent-of-Origin-Dependent and -Independent Manners
Alves da Silva A, Machado F, Pavarino E, Biselli-Perico J, Zampieri B, da Silva Francisco Junior R, et al.
PLoS One . 2016 Apr; 11(4):e0154108. PMID: 27100087
The supernumerary chromosome 21 in Down syndrome differentially affects the methylation statuses at CpG dinucleotide sites and creates genome-wide transcriptional dysregulation of parental alleles, ultimately causing diverse pathologies. At present,...
3.
Novel microduplications at Xp11.22 including HUWE1: clinical and molecular insights into these genomic rearrangements associated with intellectual disability
Santos-Reboucas C, Guedes de Almeida L, Belet S, Dos Santos S, Ribeiro M, Alves da Silva A, et al.
J Hum Genet . 2015 Feb; 60(4):207-11. PMID: 25652354
Recently, we defined a minimal overlapping region for causal Xp11.22 copy number gains in males with intellectual disability (ID), and identified HECT, UBA and WWE domain-containing protein-1 (HUWE1) as the...
4.
5meCpG epigenetic marks neighboring a primate-conserved core promoter short tandem repeat indicate X-chromosome inactivation
Machado F, Machado F, Faria M, Lamim Lovatel V, Alves da Silva A, Radic C, et al.
PLoS One . 2014 Aug; 9(7):e103714. PMID: 25078280
X-chromosome inactivation (XCI) is the epigenetic transcriptional silencing of an X-chromosome during the early stages of embryonic development in female eutherian mammals. XCI assures monoallelic expression in each cell and...
5.
A novel in-frame deletion affecting the BAR domain of OPHN1 in a family with intellectual disability and hippocampal alterations
Santos-Reboucas C, Belet S, Guedes de Almeida L, Ribeiro M, Medina-Acosta E, Bahia P, et al.
Eur J Hum Genet . 2013 Oct; 22(5):644-51. PMID: 24105372
Oligophrenin-1 (OPHN1) is one of at least seven genes located on chromosome X that take part in Rho GTPase-dependent signaling pathways involved in X-linked intellectual disability (XLID). Mutations in OPHN1...