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Antonio Campos Jr

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Articles 16
Citations 274
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Recent Articles
1.
Jia L, Rafiq M, Radosa L, Hortschansky P, Cunha C, Cseresnyes Z, et al.
Cell Host Microbe . 2023 Mar; 31(3):373-388.e10. PMID: 36893734
The decision whether endosomes enter the degradative or recycling pathway in mammalian cells is of fundamental importance for pathogen killing, and its malfunctioning has pathological consequences. We discovered that human...
2.
Matzaraki V, Beno A, Jaeger M, Gresnigt M, Keur N, Boahen C, et al.
Redox Biol . 2022 Jul; 55:102391. PMID: 35834984
Reactive oxygen species (ROS) are an essential component of the host defense against fungal infections. However, little is known about how common genetic variation affects ROS-mediated antifungal host defense. In...
3.
Wang X, Cunha C, Grau M, Robertson S, Lacerda J, Campos Jr A, et al.
J Immunol . 2022 Jun; 209(2):346-353. PMID: 35750336
Our recent data demonstrate a critical role of the RIG-I-like receptor family in regulating antifungal immunity against in a murine model. However, the importance of this pathway in humans and...
4.
Doni A, Parente R, Laface I, Magrini E, Cunha C, Colombo F, et al.
Nat Commun . 2021 Jun; 12(1):3739. PMID: 34145258
Serum amyloid P component (SAP, also known as Pentraxin 2; APCS gene) is a component of the humoral arm of innate immunity involved in resistance to bacterial infection and regulation...
5.
Goncalves S, Antunes D, Leite L, Mercier T, Ter Horst R, Vieira J, et al.
mBio . 2021 May; 12(3):e0036921. PMID: 34044589
Activation of immune cells in response to fungal infection involves the reprogramming of their cellular metabolism to support antimicrobial effector functions. Although metabolic pathways such as glycolysis are known to...
6.
Schmidt F, Thywissen A, Goldmann M, Cunha C, Cseresnyes Z, Schmidt H, et al.
Cell Rep . 2020 Aug; 32(7):108017. PMID: 32814035
Lipid rafts form signaling platforms on biological membranes with incompletely characterized role in immune response to infection. Here we report that lipid-raft microdomains are essential components of phagolysosomal membranes of...
7.
Goncalves S, Duarte-Oliveira C, Campos C, Aimanianda V, Ter Horst R, Leite L, et al.
Nat Commun . 2020 May; 11(1):2282. PMID: 32385235
In response to infection, macrophages adapt their metabolism rapidly to enhance glycolysis and fuel specialized antimicrobial effector functions. Here we show that fungal melanin is an essential molecule required for...
8.
Campos C, Leite L, Pereira P, Vaz C, Branca R, Campilho F, et al.
Front Immunol . 2019 Feb; 10:88. PMID: 30766534
Reactivation of latent human cytomegalovirus (CMV) in patients undergoing allogeneic stem-cell transplantation (HSCT) predisposes to several clinical complications and is therefore a major cause of morbidity and mortality. Although pentraxin-3...
9.
Marinho-Dias J, Baldaque I, Pinho-Vaz C, Leite L, Branca R, Campilho F, et al.
Mol Med Rep . 2018 Dec; 19(3):1435-1442. PMID: 30592278
The identification of patients at higher risk of developing Epstein‑Barr virus (EBV) infection in hematopoietic stem cell transplants (HSCT) is useful for the prevention of EBV‑associated diseases A prospective observational...
10.
Marinho-Dias J, Lobo J, Henrique R, Baldaque I, Pinho-Vaz C, Regadas L, et al.
Mol Med Rep . 2018 Sep; 18(5):4650-4656. PMID: 30221663
Post‑transplant lymphoproliferative disorder (PTLD), despite its rarity, is an important mortality/morbidity event in transplant patients. The purpose of the present study was to retrospectively examine the clinical and pathologic characteristics,...