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Antonia Castilho

Explore the profile of Antonia Castilho including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 587
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Recent Articles
1.
Lee T, Castilho A, Cheung V, Tang K, Ma S, Ng I
Cell Stem Cell . 2011 Jul; 9(1):50-63. PMID: 21726833
Tumor-initiating cells (T-ICs) are a subpopulation of chemoresistant tumor cells that have been shown to cause tumor recurrence upon chemotherapy. Identification of T-ICs and their related pathways are therefore priorities...
2.
Ma S, Tang K, Chan Y, Lee T, Kwan P, Castilho A, et al.
Cell Stem Cell . 2010 Nov; 7(6):694-707. PMID: 21112564
A novel paradigm in tumor biology suggests that cancer growth is driven by stem-like cells within a tumor, called tumor-initiating cells (TICs) or cancer stem cells (CSCs). Here we describe...
3.
Lee T, Castilho A, Cheung V, Tang K, Ma S, Ng I
Hepatology . 2010 Oct; 53(1):160-70. PMID: 20979057
Unlabelled: Liver tumor-initiating cells (T-ICs) are capable of self-renewal and tumor initiation and are more chemoresistant to chemotherapeutic drugs. The current therapeutic strategies for targeting stem cell self-renewal pathways therefore...
4.
Lee T, Castilho A, Ma S, Ng I
Liver Int . 2009 Jun; 29(7):955-65. PMID: 19490415
Hepatocellular carcinoma (HCC) is an aggressive tumour with a poor prognosis. Current therapeutic strategies against this disease target mostly rapidly growing differentiated tumour cells. However, the result is often dismal...