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Anton Golovnin

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Articles 22
Citations 364
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Recent Articles
1.
Melnikova L, Molodina V, Georgiev P, Golovnin A
Int J Mol Sci . 2024 May; 25(9). PMID: 38731837
Chromatin architecture is critical for the temporal and tissue-specific activation of genes that determine eukaryotic development. The functional interaction between enhancers and promoters is controlled by insulators and tethering elements...
2.
Melnikova L, Golovnin A
Int J Mol Sci . 2023 Nov; 24(22). PMID: 38003676
The dADD1 and dXNP proteins are orthologues of the ADD and SNF2 domains of the vertebrate ATRX (Alpha-Thalassemia with mental Retardation X-related) protein. ATRX plays a role in general molecular...
3.
Golovnin A, Melnikova L, Babosha V, Pokholkova G, Slovohotov I, Umnova A, et al.
Int J Mol Sci . 2023 Nov; 24(21). PMID: 37958900
CP190 is a co-factor in many architectural proteins, being involved in the formation of active promoters and insulators. CP190 contains the N-terminal BTB/POZ (Broad-Complex, Tramtrack and Bric a brac/POxvirus and...
4.
Melnikova L, Molodina V, Babosha V, Kostyuchenko M, Georgiev P, Golovnin A
Int J Mol Sci . 2023 Oct; 24(19). PMID: 37834476
Drosophila CP190 and CP60 are transcription factors that are associated with centrosomes during mitosis. CP190 is an essential transcription factor and preferentially binds to housekeeping gene promoters and insulators through...
5.
Melnikova L, Molodina V, Erokhin M, Georgiev P, Golovnin A
Sci Rep . 2019 Dec; 9(1):19102. PMID: 31836797
Suppressor of Hairy-wing [Su(Hw)] is one of the best characterized architectural proteins in Drosophila and recruits the CP190 and Mod(mdg4)-67.2 proteins to chromatin, where they form a well-known insulator complex....
6.
Melnikova L, Elizarev P, Erokhin M, Molodina V, Chetverina D, Kostyuchenko M, et al.
Sci Rep . 2019 Mar; 9(1):5314. PMID: 30926937
Suppressor of Hairy-wing [Su(Hw)] is a DNA-binding architectural protein that participates in the organization of insulators and repression of promoters in Drosophila. This protein contains acidic regions at both ends...
7.
Melnikova L, Kostyuchenko M, Parshikov A, Georgiev P, Golovnin A
PLoS One . 2018 Feb; 13(2):e0193497. PMID: 29474480
Su(Hw) belongs to the class of proteins that organize chromosome architecture and boundaries/insulators between regulatory domains. This protein contains a cluster of 12 zinc finger domains most of which are...
8.
Melnikova L, Kostyuchenko M, Molodina V, Parshikov A, Georgiev P, Golovnin A
Open Biol . 2017 Oct; 7(10). PMID: 29021216
The best-studied insulator complex consists of two BTB-containing proteins, the Mod(mdg4)-67.2 isoform and CP190, which are recruited to the chromatin through interactions with the DNA-binding Su(Hw) protein. It was shown...
9.
Melnikova L, Kostyuchenko M, Molodina V, Parshikov A, Georgiev P, Golovnin A
Chromosoma . 2017 Sep; 127(1):59-71. PMID: 28939920
The best-studied Drosophila insulator complex consists of two BTB-containing proteins, the Mod(mdg4)-67.2 isoform and CP190, which are recruited cooperatively to chromatin through interactions with the DNA-binding architectural protein Su(Hw). While...
10.
Melnikova L, Shapovalov I, Kostyuchenko M, Georgiev P, Golovnin A
Chromosoma . 2016 May; 126(2):299-311. PMID: 27136940
Recent data suggest that insulators organize chromatin architecture in the nucleus. The best characterized Drosophila insulator, found in the gypsy retrotransposon, contains 12 binding sites for the Su(Hw) protein. Enhancer...