Anthony J Burt
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Explore the profile of Anthony J Burt including associated specialties, affiliations and a list of published articles.
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3
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12
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Recent Articles
1.
Pulukuri A, Burt A, Opp L, McDowell C, Davaritouchaee M, Nielsen A, et al.
Pharmaceuticals (Basel)
. 2021 Dec;
14(12).
PMID: 34959691
Multidrug-Resistant (MDR) cancers attenuate chemotherapeutic efficacy through drug efflux, a process that transports drugs from within a cell to the extracellular space via ABC (ATP-Binding Cassette) transporters, including P-glycoprotein 1...
2.
Ryan A, Pulukuri A, Davaritouchaee M, Abbasi A, Hendricksen A, Opp L, et al.
Acta Pharmacol Sin
. 2020 May;
41(7):995-1004.
PMID: 32451412
We have recently developed an enzyme-directed immunostimulant (EDI) prodrug motif, which is metabolized to active immunostimulant by cancer cells and, following drug efflux, activates nearby immune cells, resulting in immunogenicity....
3.
Burt A, Hantho J, Nielsen A, Mancini R
Biochemistry
. 2018 Mar;
57(15):2184-2188.
PMID: 29553720
Drug efflux and enzymatic drug degradation are two cellular mechanisms that contribute to drug resistance in many cancers. Herein, we report the synthesis and in vitro activity of a pro-immunostimulant...