Anookh Mohanan
Overview
Explore the profile of Anookh Mohanan including associated specialties, affiliations and a list of published articles.
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6
Citations
61
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Recent Articles
1.
Joshi D, Gj P, Ghosh S, Mohanan A, Joshi S, Mohan V, et al.
Diabetes Metab Syndr Obes
. 2022 Mar;
15:615-631.
PMID: 35241920
Background: TRC150094, a novel mitochondrial modulator, reduces insulin resistance and is expected to improve the trinity of dysglycemia, dyslipidemia, and hypertension. In this multi-dose phase-2 study, we evaluated the safety...
2.
Joshi D, Jamadarkhana P, Kumbhare S, Singh A, Kotecha J, Bunger D, et al.
Front Pharmacol
. 2021 Oct;
12:729424.
PMID: 34603045
TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral...
3.
van der Valk F, Hassing C, Visser M, Thakkar P, Mohanan A, Pathak K, et al.
PLoS One
. 2014 Mar;
9(2):e86890.
PMID: 24586256
Background And Aims: Obesity and its associated cardiometabolic co-morbidities are increasing worldwide. Since thyroid hormone mimetics are capable of uncoupling the beneficial metabolic effects of thyroid hormones from their deleterious...
4.
Jamadarkhana P, Chaudhary A, Chhipa L, Dubey A, Mohanan A, Gupta R, et al.
Am J Nephrol
. 2012 Sep;
36(3):208-18.
PMID: 22948183
Background: Hypoxia-inducible factor (HIF) transcriptional system plays a central role in cellular adaptation to low oxygen levels. Preconditional activation of HIF and/or expression of its individual target gene products leading...
5.
Mohanan A, Gupta R, Dubey A, Jagtap V, Mandhare A, Gupta R, et al.
Int J Hypertens
. 2012 Jan;
2011:751513.
PMID: 22235363
In hypertensive subjects, angiotensin II and endothelin participate in a manner involving closely interwoven pathways in increasing blood pressure (BP) and inducing end organ damage. The primary objective of this...
6.
Mohanan A, Deshpande S, Jamadarkhana P, Kumar P, Gupta R, Chauthaiwale V, et al.
Neuropharmacology
. 2010 Dec;
60(6):991-9.
PMID: 21167846
Induction of HSPs is a natural response of stressed cells that protects against many insults including acute ischemia. TRC051384, a novel compound belonging to substituted 2-propen-1-one class is a potent...