Annie Eis
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Explore the profile of Annie Eis including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
536
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Recent Articles
1.
Dahal N, Sharma S, Phan B, Eis A, Popa I
Sci Adv
. 2022 Jul;
8(28):eabl7719.
PMID: 35857491
Talin is a force-sensing multidomain protein and a major player in cellular mechanotransduction. Here, we use single-molecule magnetic tweezers to investigate the mechanical response of the R8 rod domain of...
2.
Adhikari D, Biener G, Stoneman M, Badu D, Paprocki J, Eis A, et al.
Spectrochim Acta A Mol Biomol Spectrosc
. 2021 Jul;
262:120133.
PMID: 34243141
Understanding the photophysical properties of fluorescent proteins (FPs), such as emission and absorption spectra, molecular brightness, photostability, and photo-switching, is critical to the development of criteria for their selection as...
3.
Dahal N, Nowitzke J, Eis A, Popa I
J Phys Chem B
. 2020 Feb;
124(16):3283-3290.
PMID: 32097002
Binding-induced mechanical stabilization plays key roles in proteins involved in muscle contraction, cellular mechanotransduction, or bacterial adhesion. Because of the vector nature of force, single-molecule force spectroscopy techniques are ideal...
4.
Stoneman M, Biener G, Ward R, Pediani J, Badu D, Eis A, et al.
Nat Methods
. 2019 May;
16(6):493-496.
PMID: 31110281
Here, we introduce fluorescence intensity fluctuation spectrometry for determining the identity, abundance and stability of protein oligomers. This approach was tested on monomers and oligomers of known sizes and was...
5.
Khoury L, Nowitzke J, Dahal N, Shmilovich K, Eis A, Popa I
J Vis Exp
. 2018 Sep;
(138).
PMID: 30199039
Here, we describe a force-clamp rheometry method to characterize the biomechanical properties of protein-based hydrogels. This method uses an analog proportional-integral-derivative (PID) system to apply controlled-force protocols on cylindrical protein-based...
6.
Afolayan A, Eis A, Alexander M, Michalkiewicz T, Teng R, Lakshminrusimha S, et al.
Am J Physiol Lung Cell Mol Physiol
. 2015 Nov;
310(1):L40-9.
PMID: 26519208
Impaired vasodilation in persistent pulmonary hypertension of the newborn (PPHN) is characterized by mitochondrial dysfunction. We investigated the hypothesis that a decreased endothelial nitric oxide synthase level leads to impaired...
7.
Konduri G, Afolayan A, Eis A, Pritchard Jr K, Teng R
Am J Physiol Lung Cell Mol Physiol
. 2015 Aug;
309(9):L1009-17.
PMID: 26320159
An increase in oxygen tension at birth is one of the key signals that initiate pulmonary vasodilation in the fetal lung. We investigated the hypothesis that targeting endothelial nitric oxide...
8.
Mahajan C, Afolayan A, Eis A, Teng R, Konduri G
Pediatr Res
. 2014 Dec;
77(3):455-62.
PMID: 25521916
Background: Persistent pulmonary hypertension of the newborn (PPHN) is associated with decreased lung angiogenesis and impaired pulmonary vasodilatation at birth. Prostanoids are important modulators of vascular tone and angiogenesis. We...
9.
Afolayan A, Teng R, Eis A, Rana U, Broniowska K, Corbett J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2013 Dec;
306(4):L351-60.
PMID: 24375796
Superoxide dismutase 2 (SOD-2) is synthesized in the cytosol and imported into the mitochondrial matrix, where it is activated and functions as the primary antioxidant for cellular respiration. The specific...
10.
Konduri G, Bakhutashvili I, Eis A, Afolayan A
Pediatr Res
. 2013 Feb;
73(5):621-9.
PMID: 23370411
Background: Persistent pulmonary hypertension of the newborn (PPHN) is associated with increased oxidative stress in pulmonary arteries (PAs). Betamethasone decreases the oxidative stress and improves antioxidant balance in PPHN. We...