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Annerose E Ziegler

Explore the profile of Annerose E Ziegler including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 131
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Recent Articles
1.
Hermanussen L, Lampalzer S, Bockmann J, Ziegler A, Piecha F, Dandri M, et al.
Front Med (Lausanne) . 2023 Jun; 10:1169096. PMID: 37387781
Infections with hepatotropic viruses are associated with various immune phenomena. Hepatitis D virus (HDV) causes the most severe form of viral hepatitis. However, few recent data are available on non-disease-specific...
2.
Ziegler A, Fittje P, Muller L, Ahrenstorf A, Hagemann K, Hagen S, et al.
Front Immunol . 2023 Feb; 14:1117320. PMID: 36845105
The crosstalk between NK cells and their surrounding environment is enabled through activating and inhibitory receptors, which tightly control NK cell activity. The co-inhibitory receptor TIGIT decreases NK cell cytotoxicity...
3.
Poch T, Krause J, Casar C, Liwinski T, Glau L, Kaufmann M, et al.
J Hepatol . 2021 Mar; 75(2):414-423. PMID: 33774059
Background & Aims: Little is known about the composition of intrahepatic immune cells and their contribution to the pathogenesis of primary sclerosing cholangitis (PSC). Herein, we aimed to create an...
4.
Hess L, Martrus G, Ziegler A, Langeneckert A, Salzberger W, Goebels H, et al.
Hepatol Commun . 2020 Mar; 4(3):409-424. PMID: 32140657
The transcription factor promyelocytic leukemia zinc finger protein (PLZF) is involved in the development of natural killer (NK) cells and innate lymphoid cells, including liver-resident NK cells in mice. In...
5.
Martrus G, Goebels H, Langeneckert A, Kah J, Flomm F, Ziegler A, et al.
Front Immunol . 2019 Jun; 10:1247. PMID: 31231382
Macrophages play central roles in inflammatory reactions and initiation of immune responses during infections. More than 80% of total tissue macrophages are described to be located in the liver as...
6.
Ravichandran G, Neumann K, Berkhout L, Weidemann S, Langeneckert A, Schwinge D, et al.
J Hepatol . 2019 Jun; 71(4):773-782. PMID: 31173810
Background And Aims: Primary sclerosing cholangitis (PSC) is an idiopathic, chronic cholestatic liver disorder characterized by biliary inflammation and fibrosis. Increased numbers of intrahepatic interferon-γ- (IFNγ) producing lymphocytes have been...
7.
Langeneckert A, Lunemann S, Martrus G, Salzberger W, Hess L, Ziegler A, et al.
Eur J Immunol . 2019 Feb; 49(5):758-769. PMID: 30785638
The pathogenesis of primary sclerosing cholangitis (PSC), an autoimmune liver disease, remains unknown. The aim of this study was to characterize peripheral blood and intrahepatic NK cells from patients with...
8.
Lunemann S, Langeneckert A, Martrus G, Hess L, Salzberger W, Ziegler A, et al.
J Leukoc Biol . 2019 Feb; 105(6):1331-1340. PMID: 30779432
NK cells have been implicated to affect the outcome of numerous liver diseases. In particular, members of the killer-cell Ig-like receptor (KIR) family, predominantly expressed by NK cells, have been...
9.
Lunemann S, Schobel A, Kah J, Fittje P, Holzemer A, Langeneckert A, et al.
Gastroenterology . 2018 Jul; 155(5):1366-1371.e3. PMID: 30031767
Killer-cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer (NK) cells. Binding of KIR3DS1 to its recently discovered ligand, HLA-F, activates NK cells and has been associated with...