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Anne Kristine Anstensrud

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Citations 193
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Recent Articles
1.
Hunt T, Traaen G, Aakeroy L, Massey R, Bendz C, Overland B, et al.
Open Heart . 2024 Oct; 11(2). PMID: 39477342
Background: Obstructive sleep apnoea (OSA) can cause left atrial (LA) and left ventricular (LV) remodelling, which is linked to atrial fibrillation (AF). Whether continuous positive airway pressure (CPAP) can reverse...
2.
Woxholt S, Ueland T, Aukrust P, Anstensrud A, Broch K, Tollefsen I, et al.
Int J Cardiol . 2024 Oct; 418:132613. PMID: 39374793
Background: Tocilizumab improves myocardial salvage in ST-elevation myocardial infarction (STEMI) patients when administered before percutaneous coronary intervention (PCI). The mechanisms underlying ischemia-reperfusion injury remain unclear. In this sub-study, we investigated...
3.
Kindberg K, Broch K, Andersen G, Anstensrud A, Akra S, Woxholt S, et al.
JACC Adv . 2024 Sep; 3(9):101193. PMID: 39247678
Background: Interleukin-6-receptor inhibition with tocilizumab improves myocardial salvage in patients with ST-segment elevation myocardial infarction (STEMI). Reduced levels of neutrophil extracellular traps (NETs), which consist of nuclear material studded with...
4.
Holme F, Huse C, Kong X, Broch K, Gullestad L, Anstensrud A, et al.
Int J Mol Sci . 2024 Aug; 25(16). PMID: 39201700
Circular (circ) RNAs are non-coding RNAs with important functions in the nervous system, cardiovascular system, and cancer. Their role in atherosclerosis and myocardial infarction (MI) remains poorly described. We aim...
5.
Woxholt S, Ueland T, Aukrust P, Anstensrud A, Broch K, Tollefsen I, et al.
Open Heart . 2023 Aug; 10(2). PMID: 37591633
Background: Tocilizumab improves myocardial salvage index (MSI) in patients with ST-elevation myocardial infarction (STEMI), but its mechanisms of action are unclear. Here, we explored how cytokines were affected by tocilizumab...
6.
Huse C, Anstensrud A, Michelsen A, Ueland T, Broch K, Woxholt S, et al.
EBioMedicine . 2022 May; 80:104013. PMID: 35504178
Background: We recently showed that interleukin (IL)-6 inhibition by tocilizumab improves myocardial salvage in ST-elevation myocardial infarction (STEMI). However, the mechanisms for this effect are not clear. Methods: In this...
7.
Broch K, Anstensrud A, Woxholt S, Andersen G, Gullestad L
J Am Coll Cardiol . 2021 Aug; 78(6):637-638. PMID: 34353542
No abstract available.
8.
Broch K, Anstensrud A, Woxholt S, Sharma K, Tollefsen I, Bendz B, et al.
J Am Coll Cardiol . 2021 Apr; 77(15):1845-1855. PMID: 33858620
Background: Prompt myocardial revascularization with percutaneous coronary intervention (PCI) reduces infarct size and improves outcomes in patients with ST-segment elevation myocardial infarction (STEMI). However, as much as 50% of the...
9.
Anstensrud A, Molden E, Haug H, Qazi R, Muriq H, Fosshaug L, et al.
Eur J Clin Pharmacol . 2020 Jan; 76(5):673-683. PMID: 31940084
Purpose: The β-1 adrenergic receptor blocker metoprolol is primarily metabolized by the polymorphic enzyme cytochrome P 450 2D6 (CYP2D6), an enzyme with substantial genetic heterogeneity. Our purpose was to investigate...
10.
Anstensrud A, Woxholt S, Sharma K, Broch K, Bendz B, Aakhus S, et al.
Open Heart . 2019 Nov; 6(2):e001108. PMID: 31673391
Introduction: Interleukin-6 (IL-6) may be involved in ischaemia-reperfusion injury and myocardial remodelling after myocardial infarction (MI). We have recently shown that IL-6 inhibition by tocilizumab attenuates systemic inflammation and troponin...