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Anne H Neerincx

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Citations 366
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Recent Articles
11.
Kos R, Neerincx A, Fenn D, Brinkman P, Lub R, Vonk S, et al.
Pharmacol Res Perspect . 2022 Nov; 10(6):e01015. PMID: 36440690
Elexacaftor/tezacaftor/ivacaftor (ETI) is a cystic fibrosis (CF) transmembrane conductance regulator modulator, which has shown efficacy in CF patients (≥6 years) with ≥1 Phe508del mutation and a minimal function mutation. In...
12.
Kos R, Israels J, van Gogh C, Altenburg J, Diepenhorst S, Paff T, et al.
Am J Med Genet C Semin Med Genet . 2022 Mar; 190(1):89-101. PMID: 35343062
Primary ciliary dyskinesia (PCD) is a heterogeneous disease, with impaired mucociliary clearance causing respiratory tract infections. A founding CCDC114 mutation has led to a relatively homogeneous and large Dutch PCD...
13.
I Abdel-Aziz M, Vijverberg S, Neerincx A, Brinkman P, Wagener A, Riley J, et al.
Eur Respir J . 2021 Nov; 59(1). PMID: 34824056
No abstract available.
14.
Fenn D, I Abdel-Aziz M, Brinkman P, Kos R, Neerincx A, Altenburg J, et al.
J Cyst Fibros . 2021 Sep; 21(1):52-60. PMID: 34548223
Background: With the continued advancement of CFTR modulator therapies there is likely to be a burgeoning population of adult cystic fibrosis (CF) patients unable to expectorate sputum. Consequently, the detection...
15.
I Abdel-Aziz M, Neerincx A, Vijverberg S, Hashimoto S, Brinkman P, Gorenjak M, et al.
J Pers Med . 2021 Jun; 11(6). PMID: 34071272
There is a clinical need to identify children with poor asthma control as early as possible, to optimize treatment and/or to find therapeutic alternatives. Here, we present the "Systems Pharmacology...
16.
Kos R, Brinkman P, Neerincx A, Paff T, Gerritsen M, Lammers A, et al.
J Cyst Fibros . 2021 May; 21(1):e28-e34. PMID: 34016557
Background: Pseudomonas aeruginosa (PA) is an important respiratory pathogen for cystic fibrosis (CF) patients. Routine microbiology surveillance is time-consuming, and is best performed on expectorated sputum. As alternative, volatile organic...
17.
Lammers A, Neerincx A, Vijverberg S, Longo C, Janssen N, Boere A, et al.
Sensors (Basel) . 2021 Apr; 21(7). PMID: 33916542
Environmental factors, such as air pollution, can affect the composition of exhaled breath, and should be well understood before biomarkers in exhaled breath can be used in clinical practice. Our...
18.
Neerincx A, Whiteson K, Phan J, Brinkman P, I Abdel-Aziz M, Weersink E, et al.
ERJ Open Res . 2021 Apr; 7(2). PMID: 33898610
Rationale: Targeted cystic fibrosis (CF) therapy with lumacaftor/ivacaftor partly restores chloride channel function and improves epithelial fluid transport in the airways. Consequently, changes may occur in the microbiome, which is...
19.
Slob E, Richards L, Vijverberg S, Longo C, Koppelman G, Pijnenburg M, et al.
Pediatr Allergy Immunol . 2021 Mar; 32(6):1197-1207. PMID: 33706416
Background: Some children with asthma experience exacerbations despite long-acting beta2-agonist (LABA) treatment. While this variability is partly caused by genetic variation, no genome-wide study until now has investigated which genetic...
20.
Lammers A, Brinkman P, Te Nijenhuis L, de Vries R, Dagelet Y, Duijvelaar E, et al.
Allergy . 2021 Mar; 76(8):2488-2499. PMID: 33704785
Background: Early detection/prediction of flare-ups in asthma, commonly triggered by viruses, would enable timely treatment. Previous studies on exhaled breath analysis by electronic nose (eNose) technology could discriminate between stable...