Anne Child
Overview
Explore the profile of Anne Child including associated specialties, affiliations and a list of published articles.
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31
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1255
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Recent Articles
1.
Iskandar Z, Dodd M, Huang J, Chin C, Stuart G, Caputo M, et al.
Eur Heart J Open
. 2023 Oct;
3(5):oead095.
PMID: 37829559
Aims: The fragmentation and loss of elastic fibre in the tunica media of the aorta are pathological hallmarks of Marfan syndrome (MFS) but the dynamics of elastin degradation and its...
2.
Davaapil H, McNamara M, Granata A, Macrae R, Hirano M, Fitzek M, et al.
Stem Cell Reports
. 2023 Jan;
18(2):555-569.
PMID: 36669494
Marfan syndrome (MFS) is a rare connective tissue disorder caused by mutations in FBN1. Patients with MFS notably suffer from aortic aneurysm and dissection. Despite considerable effort, animal models have...
3.
Salmasi M, Morris-Rosendahl D, Jarral O, Rosendahl U, Asimakopoulos G, Raja S, et al.
Int J Cardiol
. 2022 Jul;
366:1-9.
PMID: 35830949
Objectives: This study aims to identify the clinical utility of targeted-genetic sequencing in a cohort of patients with TAA and establish a new method for regional histological characterisation of TAA...
4.
Mathieu H, Spataru A, Aragon-Martin J, Child A, Barchi S, Fortin C, et al.
Genes (Basel)
. 2021 Aug;
12(7).
PMID: 34356048
Adolescent idiopathic scoliosis (AIS) is a complex common disorder of multifactorial etiology defined by a deviation of the spine in three dimensions that affects approximately 2% to 4% of adolescents....
5.
Mathieu H, Patten S, Aragon-Martin J, Ocaka L, Simpson M, Child A, et al.
Sci Rep
. 2021 May;
11(1):11026.
PMID: 34040021
Idiopathic scoliosis (IS) is a complex 3D deformation of the spine with a strong genetic component, most commonly found in adolescent girls. Adolescent idiopathic scoliosis (AIS) affects around 3% of...
6.
Mullen M, Jin X, Child A, Stuart A, Dodd M, Aragon-Martin J, et al.
Lancet
. 2019 Dec;
394(10216):2263-2270.
PMID: 31836196
Background: Irbesartan, a long acting selective angiotensin-1 receptor inhibitor, in Marfan syndrome might reduce aortic dilatation, which is associated with dissection and rupture. We aimed to determine the effects of...
7.
Isekame Y, Gati S, Aragon-Martin J, Bastiaenen R, Seshasai S, Child A
Eur Cardiol
. 2018 Oct;
11(2):102-110.
PMID: 30310455
Marfan syndrome (MFS) is a disease in which connective tissue becomes weak secondary to fibrillin-1 mutations, resulting in aortic dilatation, aneurysm formation, aortic dissection, aortic regurgitation and mitral valve prolapse....
8.
Bilkhu R, Youssefi P, Soppa G, Theodoropoulos P, Phillips S, Liban B, et al.
Ann Thorac Surg
. 2018 Apr;
106(3):771-776.
PMID: 29698663
Background: Recent guidelines support more aggressive surgery for aneurysms of the ascending aorta and root in patients with bicuspid aortic valve. However, the fate of the arch after surgery of...
9.
10.
Regalado E, Mellor-Crummey L, De Backer J, Braverman A, Ades L, Benedict S, et al.
Genet Med
. 2018 Jan;
20(10):1206-1215.
PMID: 29300374
Purpose: Smooth muscle dysfunction syndrome (SMDS) due to heterozygous ACTA2 arginine 179 alterations is characterized by patent ductus arteriosus, vasculopathy (aneurysm and occlusive lesions), pulmonary arterial hypertension, and other complications...