Anne-May Osterholm
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Explore the profile of Anne-May Osterholm including associated specialties, affiliations and a list of published articles.
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9
Citations
268
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Recent Articles
1.
Guo J, Rackham O, Sandholm N, He B, Osterholm A, Valo E, et al.
J Am Soc Nephrol
. 2020 Jan;
31(2):309-323.
PMID: 31919106
Background: Several genetic susceptibility loci associated with diabetic nephropathy have been documented, but no causative variants implying novel pathogenetic mechanisms have been elucidated. Methods: We carried out whole-genome sequencing of...
2.
Sigmundsson K, Ojala J, Ohman M, Osterholm A, Moreno-Moral A, Domogatskaya A, et al.
Matrix Biol
. 2018 Mar;
70:5-19.
PMID: 29601863
The efficacy of islet transplantation for diabetes treatment suffers from lack of cadaver-derived islets, islet necrosis and long transfer times prior to transplantation. Here, we developed a method for culturing...
3.
Sambo F, Malovini A, Sandholm N, Stavarachi M, Forsblom C, Makinen V, et al.
Diabetologia
. 2014 May;
57(8):1611-22.
PMID: 24871321
Aims/hypothesis: Diabetic nephropathy is a major diabetic complication, and diabetes is the leading cause of end-stage renal disease (ESRD). Family studies suggest a hereditary component for diabetic nephropathy. However, only...
4.
Sandholm N, Forsblom C, Makinen V, McKnight A, Osterholm A, He B, et al.
Diabetologia
. 2014 Mar;
57(6):1143-53.
PMID: 24595857
Aims/hypothesis: An abnormal urinary albumin excretion rate (AER) is often the first clinically detectable manifestation of diabetic nephropathy. Our aim was to estimate the heritability and to detect genetic variation...
5.
He B, Osterholm A, Ojala J, Andersson A, Tryggvason K
PLoS One
. 2013 Feb;
8(2):e56414.
PMID: 23441190
We have previously reported genetic association of a single nucleotide polymorphism (SNP), rs1866813, at 3q locus with increased risk of diabetic nephropathy (DN). The SNP is located approximately 70 kb...
6.
Sandholm N, Salem R, McKnight A, Brennan E, Forsblom C, Isakova T, et al.
PLoS Genet
. 2012 Oct;
8(9):e1002921.
PMID: 23028342
Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation. In...
7.
Williams W, Salem R, McKnight A, Sandholm N, Forsblom C, Taylor A, et al.
Diabetes
. 2012 Jun;
61(8):2187-94.
PMID: 22721967
We formed the GEnetics of Nephropathy-an International Effort (GENIE) consortium to examine previously reported genetic associations with diabetic nephropathy (DN) in type 1 diabetes. GENIE consists of 6,366 similarly ascertained...
8.
He B, Osterholm A, Hoverfalt A, Forsblom C, Hjorleifsdottir E, Nilsson A, et al.
Am J Hum Genet
. 2008 Dec;
84(1):5-13.
PMID: 19084216
Diabetic nephropathy (DN) is the primary cause of morbidity and mortality in patients with type 1 diabetes mellitus (T1DM) and affects about 30% of these patients. We have previously localized...
9.
Qiao Q, Osterholm A, He B, Pitkaniemi J, Cordell H, Sarti C, et al.
BMC Genet
. 2007 Dec;
8:84.
PMID: 18093291
Background: A genome-wide search for genes that predispose to type 1 diabetes using linkage analysis was performed using 900 microsatellite markers in 70 nuclear families with affected siblings from Finland,...