Anne-Marie Mir
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Explore the profile of Anne-Marie Mir including associated specialties, affiliations and a list of published articles.
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22
Citations
449
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Recent Articles
1.
Chang L, Teppa E, Noel M, Gilormini P, Decloquement M, Lion C, et al.
Int J Mol Sci
. 2019 Feb;
20(3).
PMID: 30709055
The mammalian mono-α2,8-sialyltransferase ST8Sia VI has been shown to catalyze the transfer of a unique sialic acid residues onto core 1 -glycans leading to the formation of di-sialylated -glycosylproteins and...
2.
Krzewinski-Recchi M, Potelle S, Mir A, Vicogne D, Dulary E, Duvet S, et al.
Biochim Biophys Acta Gen Subj
. 2017 Jan;
1861(4):737-748.
PMID: 28088503
Background: Defects in TMEM165 gene cause a type-II Congenital Disorder of Glycosylation affecting Golgi glycosylation processes. TMEM165 patients exhibit psychomotor retardation, important osteoporosis, scoliosis, irregular epiphyses and thin bone cortex....
3.
Baldini S, Steenackers A, Olivier-Van Stichelen S, Mir A, Mortuaire M, Lefebvre T, et al.
Biochem Biophys Res Commun
. 2016 Aug;
478(2):942-8.
PMID: 27520373
Blood glucose fluctuates with the fasting-feeding cycle. One of the liver's functions is to maintain blood glucose concentrations within a physiological range. Glucokinase (GCK) or hexokinase IV, is the main...
4.
Gatta E, Lefebvre T, Gaetani S, Dos Santos M, Marrocco J, Mir A, et al.
Pharmacol Res
. 2016 Jan;
105:186-97.
PMID: 26816085
Intracellular accumulation of hyperphosphorylated tau protein is linked to neuronal degeneration in Alzheimer's disease (AD). Mounting evidence suggests that tau phosphorylation and O-N-acetylglucosamine glycosylation (O-GlcNAcylation) are mutually exclusive post-translational modifications....
5.
Petit D, Teppa E, Mir A, Vicogne D, Thisse C, Thisse B, et al.
Mol Biol Evol
. 2014 Dec;
32(4):906-27.
PMID: 25534026
Sialyltransferases are responsible for the synthesis of a diverse range of sialoglycoconjugates predicted to be pivotal to deuterostomes' evolution. In this work, we reconstructed the evolutionary history of the metazoan...
6.
Vercoutter-Edouart A, El Yazidi-Belkoura I, Guinez C, Baldini S, Leturcq M, Mortuaire M, et al.
Proteomics
. 2014 Nov;
15(5-6):1039-50.
PMID: 25429863
O-GlcNAcylation (O-linked beta-N-acetylglucosaminylation) is a widespread PTM confined within the nuclear, the cytosolic, and the mitochondrial compartments of eukaryotes. Recently, O-GlcNAcylation has been also detected in the close vicinity of...
7.
O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41
Olivier-Van Stichelen S, Dehennaut V, Buzy A, Zachayus J, Guinez C, Mir A, et al.
FASEB J
. 2014 Apr;
28(8):3325-38.
PMID: 24744147
Dysfunctions in Wnt signaling increase β-catenin stability and are associated with cancers, including colorectal cancer. In addition, β-catenin degradation is decreased by nutrient-dependent O-GlcNAcylation. Human colon tumors and colons from...
8.
Peanne R, Vanbeselaere J, Vicogne D, Mir A, Biot C, Matthijs G, et al.
Methods Cell Biol
. 2013 Dec;
118:157-76.
PMID: 24295306
Modifications of N-glycosylation in disease states are common and illustrate the crucial requirement of glycosylation in human biology. Mainly based on glycan permethylation and the use of mass spectrometry analysis,...
9.
Olivier-Van Stichelen S, Guinez C, Mir A, Perez-Cervera Y, Liu C, Michalski J, et al.
Am J Physiol Endocrinol Metab
. 2011 Nov;
302(4):E417-24.
PMID: 22114026
The short half-life protooncogene β-catenin acquires a remarkable stability in a large subset of cancers, mainly from mutations affecting its proteasomal degradation. In this sense, colorectal cancers (CRC) form a...
10.
Olivier S, Mir A, Michalski J, Lefebvre T
Med Sci (Paris)
. 2011 May;
27(5):514-20.
PMID: 21609673
The setting up and the progression of the colorectal cancer (CCR) follow a sequence of events that are spatio-temporally rigorously orchestrated. The failures that specifically target the signaling pathways responsible...