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Annalaura Montella

Explore the profile of Annalaura Montella including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 156
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Recent Articles
1.
Giugliano G, Pirone D, Behal J, Wang Z, Cerbone V, Mugnano M, et al.
J Opt Soc Am A Opt Image Sci Vis . 2025 Jan; 41(12):2421-2429. PMID: 39889107
This study presents an innovative methodology to analyze a blood sample from a healthy donor, providing a quantitative characterization of white blood cells (WBCs). It aims to evaluate the effectiveness...
2.
Montella A, Tirelli M, Lasorsa V, Aievola V, Cerbone V, Manganiello R, et al.
Br J Cancer . 2025 Jan; 132(5):469-480. PMID: 39843641
Background: Emerging evidence suggests that non-coding somatic single nucleotide variants (SNVs) in cis-regulatory elements (CREs) contribute to cancer by disrupting gene expression networks. However, the role of non-coding SNVs in...
3.
Tirelli M, Bonfiglio F, Cantalupo S, Montella A, Avitabile M, Maiorino T, et al.
Hum Genet . 2024 Aug; 143(11):1293-1309. PMID: 39192051
Genome-Wide Association Studies (GWAS) have been decisive in elucidating the genetic predisposition of neuroblastoma (NB). The majority of genetic variants identified in GWAS are found in non-coding regions, suggesting that...
4.
Floris M, Moschella A, Alcalay M, Montella A, Tirelli M, Fontana L, et al.
Hum Genomics . 2024 Jul; 18(1):78. PMID: 38987819
Pharmacogenetics investigates sequence of genes that affect drug response, enabling personalized medication. This approach reduces drug-induced adverse reactions and improves clinical effectiveness, making it a crucial consideration for personalized medical...
5.
Montella A, Cantalupo S, DAlterio G, Damiano V, Iolascon A, Capasso M
Explor Target Antitumor Ther . 2024 May; 5(2):374-383. PMID: 38745766
Fluoropyrimidines, crucial in cancer treatment, often cause toxicity concerns even at standard doses. Toxic accumulation of fluoropyrimidine metabolites, culminating in adverse effects, can stem from impaired dihydropyrimidine dehydrogenase (DPYD) enzymatic...
6.
Pirone D, Montella A, Sirico D, Mugnano M, Del Giudice D, Kurelac I, et al.
APL Bioeng . 2023 Sep; 7(3):036118. PMID: 37753527
To efficiently tackle certain tumor types, finding new biomarkers for rapid and complete phenotyping of cancer cells is highly demanded. This is especially the case for the most common pediatric...
7.
Pirone D, Montella A, Sirico D, Mugnano M, Villone M, Bianco V, et al.
Sci Rep . 2023 Apr; 13(1):6042. PMID: 37055398
Image-based identification of circulating tumor cells in microfluidic cytometry condition is one of the most challenging perspectives in the Liquid Biopsy scenario. Here we show a machine learning-powered tomographic phase...
8.
Pirone D, Lim J, Merola F, Miccio L, Mugnano M, Bianco V, et al.
Nat Photonics . 2022 Dec; 16(12):851-859. PMID: 36451849
Quantitative Phase Imaging (QPI) has gained popularity in bioimaging because it can avoid the need for cell staining, which in some cases is difficult or impossible. However, as a result,...
9.
Cimmino F, Montella A, Tirelli M, Avitabile M, Lasorsa V, Visconte F, et al.
Cancer Cell Int . 2022 Apr; 22(1):174. PMID: 35488346
Background: FGFR1 regulates cell-cell adhesion and extracellular matrix architecture and acts as oncogene in several cancers. Potential cancer driver mutations of FGFR1 occur in neuroblastoma (NB), a neural crest-derived pediatric...
10.
Lasorsa V, Montella A, Cantalupo S, Tirelli M, de Torres C, Aveic S, et al.
Cancer Res . 2022 Feb; 82(7):1193-1207. PMID: 35101866
Significance: Assessment of noncoding cis-regulatory variants and long-range interaction data highlight the combined effect of somatic mutations in regulatory elements in driving neuroblastoma.