Annabel E Todd
Overview
Explore the profile of Annabel E Todd including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
297
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0
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Recent Articles
1.
Reimand J, Vaquerizas J, Todd A, Vilo J, Luscombe N
Nucleic Acids Res
. 2010 Apr;
38(14):4768-77.
PMID: 20385592
Transcription factor (TF) perturbation experiments give valuable insights into gene regulation. Genome-scale evidence from microarray measurements may be used to identify regulatory interactions between TFs and targets. Recently, Hu and...
2.
Todd A, Marsden R, Thornton J, Orengo C
J Mol Biol
. 2005 Apr;
348(5):1235-60.
PMID: 15854658
The explosion in gene sequence data and technological breakthroughs in protein structure determination inspired the launch of structural genomics (SG) initiatives. An often stated goal of structural genomics is the...
3.
Watson J, Todd A, Bray J, Laskowski R, Edwards A, Joachimiak A, et al.
IUBMB Life
. 2003 Jul;
55(4-5):249-55.
PMID: 12880206
The first crucial step in any structural genomics project is the selection and prioritization of target proteins for structure determination. There may be a number of selection criteria to be...
4.
Bartlett G, Todd A, Thornton J
Methods Biochem Anal
. 2003 Mar;
44:387-407.
PMID: 12647396
No abstract available.
5.
Todd A, Orengo C, Thornton J
Structure
. 2002 Oct;
10(10):1435-51.
PMID: 12377129
To improve our understanding of the evolution of novel functions, we performed a sequence, structural, and functional analysis of homologous enzymes and nonenzymes of known three-dimensional structure. In most examples...
6.
Todd A, Orengo C, Thornton J
Trends Biochem Sci
. 2002 Aug;
27(8):419-26.
PMID: 12151227
The expectation is that any similarity in reaction chemistry shared by enzyme homologues is mediated by common functional groups conserved through evolution. However, detailed enzyme studies have revealed the flexibility...
7.
Orengo C, Bray J, Buchan D, Harrison A, Lee D, Pearl F, et al.
Proteomics
. 2002 Jan;
2(1):11-21.
PMID: 11788987
Over the last decade, there have been huge increases in the numbers of protein sequences and structures determined. In parallel, many methods have been developed for recognising similarities between these...